Carbohydrates Flashcards

1
Q

What is sucrose made of?

A

Glucose + fructose

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2
Q

What is Lactose made of ?

A

Glucose + galactose

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3
Q

What is the term gluconeogenesis?

A

Formation of glucose from other sources like lipids

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4
Q

What is the term glycolysis?

A

metabolism of glucose

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5
Q

What is the term glycogenolysis?

A

Break down of glycogen

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6
Q

What is the term Lipogenesis?

A

Conversion of carbs to fatty acids

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7
Q

What is the term Lipolysis?

A

breakdown of fatty acids

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8
Q

Which hormone increases the transport entry of glucose into tissue cells?

A

Insulin

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9
Q

Where is insulin produced?

A

Beta-cells of the islet of langerhans in the pancreas.

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10
Q

When is insulin released?

A

when glucose levels in the plasma increase.

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11
Q

Which hormone increases the plasma glucose levels?

A

Glucagon

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12
Q

Where is glucagon synthesized?

A

Pancreas - Alpha cells

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13
Q

When is glucagon secreted?

A

When plasma glucose levels are low, stress, fasting.

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14
Q

What hormones (8) are responsible for the regulation of glucose?

A
  • insulin
  • Glucagon
  • Epinephrine
  • Glucocorticooids
  • GH
  • APH & ACTH
  • Thyroxine
  • Somatostatin
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15
Q

What is the importance of glucose?

A

Primary source of energy, brain is dependant on it.

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16
Q

What is the reference range of anion gap?

A

10-20 (including potassium)
7-16 (without)

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17
Q

Describe a type 1 diabetic?

A
  • Insulin dependant due to B-cell destruction, causing sudden or on set symptoms.
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18
Q

Describe a type 2 diabetic?

A
  • Non-insulin dependent
  • Not sudden/onset
  • Life style
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19
Q

What are three main symptoms a type 1 diabetic?

A
  • Polyuria
  • Polydipsia
  • Polyphagia
20
Q

Which of the two diabetes would you expect higher ketones?

21
Q

Why does Type 2 diabetes have higher plasma glucose then type 1?

A

Because type 2 are dehydrated compared to Type 1.

Polydysia (Increased thirst)

22
Q

What are the three things the body is always trying to maintain? (In the proper order)

A
  • pressure
  • pH
  • Charge
23
Q

Why wouldn’t you use K+ in the equation (NA + K) - (Cl + HCO3).

A
  • K is highly susceptible to hemolysis
  • Small
  • Reference range for K is constant because its critical for keeping you alive.
24
Q

What is a critical high glucose level?

A

> 28 mmol/L

25
What is a critical low glucose level?
< 2 mmol/L
26
What is the reference range for fasting glucose?
4-6 mmol/L
27
What is the reference range for random glucose?
6-8 mmol/L
28
What tube do you collect a HbA1c?
EDTA
29
What clinical significance does a HbA1c have?
Corresponds to the life span of RBC (3 months). Measures glycosylated-hemoglobin.
30
What two factors can alter a HbA1c?
- Red cell Life span - Glucose levels
31
What tube do you collect a glucose in when you need STAT results?
PST
32
What tubes can you collect routine glucose tests in, when travel is not required?
PST / SST
33
When glucose is collected for testing in a remote town without a centrifuge what tube do you collect it in?
Sodium fluoride + potassium oxalate
34
What is the purpose of the Glucose tolerance test?
Done on regular fasting patients to determine diabetes, or on pregnant women to determine gestational diabetes.
35
Explain the Glucose tolerance test for 50g drink?
Done on pregnant women to determine gestational diabetes
36
What was type 1 diabetes previously known as?
Juvenile diabetes
37
what was type 2 diabetes previously known as?
Adult-onset diabetes
38
What are causes for type 1 diabetes? | What primary conditions may lead to Type 1 diabetes?
* Genetic * autoimmune disease * viruses
39
what is the cause for type 2 diabetes?
Lifestyle
40
Between type 1 and type 2 which has a deficiency of insulin?
Type 1 bc type 2 is resistant
41
Which age group is mostly affected by type 1?
youth
42
which age group is mostly affected by type 2?
adults >50
43
At what rate can a person develop type 1 and type 2 diabetes?
1: Sudden onset 2: Slow onset
44
Which of the two diabetes is prone to hyperosmolar coma?
Type 2 because they’re more dehydrated and cannot get rid of solutes. | Remeber! Type 1 is always drinking - diluted plasma.
45