Carbapenems Flashcards
1
Q
Carbapenem Coverage
A
MDR, G+, G-, Anaerobes
NO atypical, MRSA, VRE, C. Diff
Ertapenem - NO pseudomonas, Acinetobacter, Entero
2
Q
Doripenem
A
IV: 500mg Q8h
3
Q
Imipenem/Cilistatin (primaxin)
A
IV: 0.25 - 1g q6-8h
4
Q
Meropenem (Merrem)
A
IV: 0.5 - 1g Q8h
IV: 4g Q8h w/ vaborbactam (Vabomere)
5
Q
Ertapenem (Invanz)
A
IV/IM: 1g QD
6
Q
Contraindications
A
Anaphylaxis w/ beta-lactams
7
Q
Side Effects
A
Diarrhea
DRESS
seizure w/ impaired kidney (imipenem)
Incr. LFTs
8
Q
Monitoring
A
Renal function
Anaphylaxis
CBC
Incr. LFTs
9
Q
Drug Interactions
A
Decrease VAP [ ]+
Drugs that lower seizure threshold (quinolones, bupropion, tramadol, ganciclovir)
10
Q
Monobactam
A
Used when beta-lactam allergy present
Cover G-, Pseudomonas
NO G+, anaerobes
11
Q
Aztreonam (Azactam)
A
IV: 0.5 - 2g Q6-12h
12
Q
Side effects
A
Rash
GI upset
N/V/D
Incr LFTs
