Carbamates Flashcards
1
Q
What is often contained in the name of carbamates?
A
“Carb”
2
Q
What was the first successful carbamate insecticide introduced in 1956?
A
Carbaryl
3
Q
What was synthesized to mimic the structure of Ach?
A
Adicarb
-this is most toxic of the CMs
4
Q
True or False. Carbamates penetrate the CNS.
A
False.
5
Q
True or False. Carbamates do not require hepatic bioactivation.
A
True.
6
Q
What is the MOA of carbamates?
A
Reversible inhibition of acetylcholinesterase
-Competitive inhibition (mass action)
7
Q
What are the clinical signs?
A
SLUD signs Salivation Lacrimation Urination Diarrhea
