cannabis Flashcards
1
Q
what are terpenoids?
A
give cannabis its smell
2
Q
what is the bioavailability of smoked THC?
A
25%
3
Q
what is the bioavailability of ingested THC
A
6%
4
Q
What is cytochrome P450 2C9
A
in liver, metabolizes THC
5
Q
what type of receptors are cannabinoid receptors?
A
G protein coupled (Gi)
6
Q
How does THC act at CB1
A
partial agonist
7
Q
How does CBD react at CB1
A
negative allosteric modulator
8
Q
Where are CB2 mostly found
A
immune cells
9
Q
what is nabilone
A
synthetic analog of THC
partial agonist at CB1
10
Q
what dronabinol
A
trans isomer of THC for nausea
partial agonists at CB1
11
Q
what is nabiximols (sativex)
A
1:1 mixture of of THC and cannabiol
12
Q
what is rimonabant
A
inverse agonist at CB1
13
Q
what is anandamide
A
endocannabinoids
14
Q
what is 2-arachinoyl glycerol
A
endocannabinoid
15
Q
how are endocannbinoids made
A
phospholipid bilayer
