alcohol Flashcards
Where is ethanol mostly absorbed?
Small intestine
What curve represents ethanol metabolism?
linear elimination curve
What is the BAC elimination per hour?
0.015
What amount of the BAC is exhaled
1/2200
How does ethanol effect Glu-NMDA receptors?
inhibition
How does ethanol effect Ca channels?
inhibition
Describe GABAa receptors?
cys-loop ligand gates channel
heteropentameric
conducts negative ions into neurons
Describe NMDA receptors?
ionotropic Glu receptor
heterotetrameric
conducts positive currents into neurons
Why is alcohol addictive?
Release of dopamine
By what mechanism does vasodilation from EtOH consumption occur?
autonomic brainstem nuclei
What 2 permeable tissues lead to the spins
EtOH permeates cupula and endolymph
Does EtOH permeate out of cupula or endolymph first?
cupula
What is the metabolic change in energy usage caused by alcohol consumption?
brain metabolizes acetate not glucose
What is the ethanol metabolite?
acetaldehyde