Canine Parvo Flashcards
What is there to say about the Parvo family?
- DNA NAKED
- very resistant in the environment
- more species specific even though canine came from feline
- loves to replicate in dividing cells
- likes to leave large intranuclear inclusion bodies
- Hemmaglutinates RBC
- PANLEUKONPENIA
- Serology not really a thing since it’s high mortality
how does Parvo affect the super young vs older?
ravages young animals
affects bone marrow and GI of older.
So, virus presentation depends on the age of the animal
What are the 3 age related disease syndromes?
1) generalized neonatal disease
2) myocarditis syndrom in 4-8 week old puppies. Peracute death
3) Leukopenia/enteritis seen in puppies 8-12 weeks old (similar to cats but with NO cerebellar hypoplasia as seen in cats)
what happens if puppies survive the myocarditis syndrome?
they have heart issues for the rest of their life
what are the signs of leukopenia/enteriris syndrome?
vomiting!!!
then you’ll see anorexia and lethargy and diarrhea and of course dehydration.
BLOODY POOP!!
Do subclinical parvo cases exist?
YES!
Where does Parvo virus enter in the body?
oropharynx
where is the initial replication site for Parvo?
tonsils and regional LN
When does viremia occur and to which areas?
Day 2
virus then spreads to thymus, spleen and bone marrow (HIGHLY DIVIDING CELLS). DESTROY THE CELLS
What happens after viremia to lymphoid organs?
There’s acute lytic infection with necrosis.
damaged villi with thickened and inelastic intestines.
What happens to virus shedding once patient recovers from Parvo?
Parvo gone shedding STOPS
what prominent sign is associated with the heart issues with Parvo?
pulmonary edema!!
What kind of diagnostic tests with Parvo?
snap test
is vaccine failure for Parvo possible?
yes because of interference from maternal antibodies
how to control Parvo?
COMPLETE THE VACCINE SCHEDULE
Keep puppies out of recreational areas
quarantine and disinfect with NAOH
