Cancer Drugs and Chemotherapy Agents

Question 1

Alkylating Agents

Answer 1

Attaches akyl group to DNA which causes DNA strand to break, leading to cell cycle arrest and death

Question 2

Antimetabolites

Answer 2

DNA substrate analog that leads to incorrect DNA synthesis

Question 3

Alkylating Agent examples

Answer 3

Platinum compounds: Cisplatin, Carboplatin, Oxaliplatin
Nitrogen mustards: Cyclophosphamide

Question 4

Antimetabolite examples

Answer 4

Pyrimidine antagonists: Fluorouracil
Antifolates: Methotrexate, Pemetrexed

Question 5

Mitotic Inhibitors

Answer 5

Blocks cell growth by stopping mitosis

Question 6

Mitotic inhibitor examples

Answer 6

Taxanes - Docetaxel, Paclitaxel
Vinca alkaloids - Vinblastine

Question 7

Immunotherapy

Answer 7

helps the immune system recognize and attack cancer cells.

Question 8

Immunotherapy examples

Answer 8

Interleukin-2, interferon

Question 9

Monoclonal antibodies

Answer 9

proteins made in laboratories that act like antibodies, which attack only abnormal elements of cells - the abnormal enzyme that causes cancerous cells to grow out of control

Question 10

Monoclonal antibodies examples

Answer 10

cetuximab, rituximab

Question 11

Methotrexate

Answer 11

Avoid echinacea - it may damage the liver