Cancer Flashcards

1
Q

RB1 gene

A

retinoblastoma

checking for loss of red reflex, if present likely to be this tumour

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2
Q

RB1 gene risk

A

36 % get a second malignancy by 50 yo

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3
Q

P53 gene association

A

Li-Fraumeni syndrome

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4
Q

Li-Fraumeni syndrome

A
Adrenocortical carcinoma 
ALL
Sarcoma
CNS 
Early breast cancer
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5
Q

Down syndrome increases risk of which cancer

A

leukaemia

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6
Q

Wilms tumour gene

A

WT1

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7
Q

Hepatoblastoma gene

A

FAP

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8
Q

B symptoms

A
unexplained fever
flu like sx
night sweats
unexplained wt loss
pruritis 
anaemia
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9
Q

2 types of leukaemia

A

ALL 85%

AML

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10
Q

2 types of ALL

A

B cell

T cell

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11
Q

Treatment of ALL duration

A

2-3 years, dont have to stay at hospital

good prognosis

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12
Q

Treatment of AML duration

A

intensive treatment 4-6 months

in patient

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13
Q

2 types of lymphoma

A

Hodgkins

Non hodgkins

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14
Q

2 types of non-hodgkins

A
T cell (mediastinal mass) 
B cell (head and neck, abdo)
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15
Q

Hodgkins sx

A

Long Hx

+/- B sx

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16
Q

Main sx of lymphoma

A

Lymphadenopathy

Hepatosplenomegaly