Cancer Flashcards

1
Q

What is the commonest cancer in males?

A
  • prostate cancer
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2
Q

What cell type is associated with prostate cancer?

A
  • adenocarcinoma
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3
Q

If the prostate cancer affects the transitional zone what are the presenting symptoms?

A
  • changes to water works
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4
Q

If the prostate cancer affects the peripheral zone what are the presenting symptoms?

A
  • asymptomatic to start
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5
Q

Symptoms of prostate cancer?

A
  • haematuria
  • haematospermia
  • incontinence
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6
Q

What is used to diagnose prostate cancer?

A
  • PSA
  • Digital rectal examination
  • Transrectal ultrasound scan with biopsy
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7
Q

What is PSA?

A
  • normal protein released from prostate
  • used to breakdown seminal coagulum
  • raised level may indicate enlargement
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8
Q

Scoring system used in prostate cancer?

A
  • Gleason scale
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9
Q

How is prostate cancer staged

A
  • TNM
  • Gleason scale
  • MRI and bone scan
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10
Q

Treatment of low risk prostate cancer?

A
  • active surveillance
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11
Q

Treatment of high risk prostate cancer?

A
  • prostatectomy
  • radiotherapy
  • androgen suppression
  • LHRH agonist
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12
Q

Name an androgen suppression drug?

A
  • bicalutamide
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13
Q

Name a LHRH agonist drug?

A
  • Goserelin
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14
Q

Hormone therapy in prostate cancer aim to?

A
  • lower testosterone
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15
Q

Cell type in urinary bladder cancer?

A
  • transitional cell carcinoma
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16
Q

Risk factors for urinary bladder cancer?

A
  • smoking
  • occupational fumes
  • chronic bladder infections
17
Q

Red flags for bladder cancer?

A
  • painless haematuria
  • flank pain

Age > 40 in women
Age > 45 in men

18
Q

Bladder cancer investigations

A
  • CT
  • USS
  • Analysis of urine
  • TURBT (Biopsy and histology)
19
Q

Treatment of low grade bladder cancer

A
  • resection

- follow up 6mnthly for 5 yrs

20
Q

Treatment of high grade bladder cancer?

A
  • resection

- intravesical BCG

21
Q

Bladder cancer invasive into muscle treatment?

A
  • external beam radiotherapy
22
Q

Metastatic bladder cancer treatment?

A
  • cisplatin based chemotherapy
23
Q

Follow up of high risk bladder cancer?

A
  • 3 monthly for 1 year
  • 6 monthly for 5 years
  • annually for 10 years