c16 & c17 genes to proteins (translation) Flashcards

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1
Q

gene expression

A

is the entire set of processes that results in using the information stored in a gene.
Molecules or events that increase gene expression are said to exert positive control. Molecules and events that decrease gene expression are said to exert negative control.
- Whether or not an RNA gets made from the information encoded in structural sequences. It depends on the events that occur at regulatory sequences

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2
Q

regulatory proteins

A

promoters, transcription factors

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3
Q

promoters

A

promote the gene expression

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4
Q

transcription factors

A

regulate gene expression, usually by binding directly to regulatory sequences in DNA

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5
Q

activators

A
  • Activators are transcription factors that help exert positive control
    Bind to enhancers
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6
Q

repressors

A
  • Repressors are transcription factors that help exert negative control
    Bind to silencers
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7
Q

enhancers

A
  • Enhancers are regulatory sites in DNA that are involved in positive control
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8
Q

silencers

A
  • Silencers are regulatory sites in DNA that are involved in negative control
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9
Q

operon

A

A sequence of structural gene sequences whose products have related functions and that are under the control of the same promoter and other regulatory sequences, meaning that they are transcribed as a unit.

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10
Q

exons

A

expressed, they code for the amino acids found in a protein product/

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11
Q

introns

A

intervene between exons. transcribed but later removed from the mRNA prior to translation

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12
Q

positive control (over gene expression)

A

mechanisms that increase the amount of active gene product available

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13
Q

negative control (over gene expression)

A

mechanisms that decrease the amount of active gene product available

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14
Q

transcription factors

A

proteins that regulate transcription, often by binding to regulatory sequences in DNA

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15
Q

chromatin

A

the complex of DNA and histone proteins that has DNA wrapped around it

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16
Q

nucleosome

A

a group of four histone proteins that has DNA wrapped around it

17
Q

histone proteins

A

proteins that have an abundance of positively charged lysines and arginines in their primary structure, which interact with negative charges on the sugar-phosphate backbone of DNA to form nucleosomes.

18
Q

anticodon

A

a sequence of three bases found at one end of a tRNA that binds to a codon in mRNA during translation via complementary base pairing

19
Q

release factor

A

a protein that fits into the A site of a ribosome, binds to a stop codon, and interacts with the ribosome to terminate translation

20
Q

reading frame

A

the sets of three-base codons in RNA or DNA that specify the primary sequence of codons

21
Q

ribozyme

A

an RNA molecule that catalyzes a chemical reaction, analogous to enzymes, which are protein catalysts

22
Q

genetic code

A

the set of relationships between the 64 possible codons in mRNA and the amino acids that are added to a newly synthesized proteni

23
Q

codon

A

a group of three bases in an mRNA that codes for an amino acids

24
Q

start codon

A

the codon that signals where translation and thus protein synthesis begins. usually AUG and also codes for the amino acid methionine (Met).

25
Q

stop codon

A

that signals where translation and thus protein synthesis ends. usually UAA, UAG, and UGA

26
Q

endomembrane system

A

a collection of machines, cytoskeletal componenets and organelles that together produce, process, and transport proteins and lipids destined for organelles, the cell membrane, or outside th ecell

27
Q

signal sequence

A

a series of amino acids at the start of a protein that allows that protein to enter the endomembrane system

28
Q

motor protein

A

a protein that fucntion in cell movement through shape changes caused by phosphorylation or dephosphorylation

29
Q

phosphorylation

A

the addition of a phosphate group (PO4^3) to a protein or other molecule. in most cases, the phosphate group comes from ATP. Dephosphorylation is the reverse process