C12: Variation Flashcards

1
Q

3 causes of continuous variation

A

(environmental factors)

  • temperature
  • pH value
  • light
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2
Q

4 causes of discontinuous variation

A

(genetic factor)

  • crossing over
  • independent assortment of chromosomes
  • random fertilisation
  • mutation
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3
Q

why environmental factors have small effect to variation only

A
  • only involves phenotypic differences
  • change allele frequency and genotype frequency
  • not change the genotype
  • cannot be inherited
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4
Q

example of effect of temperature to variation

A
  • Siamese cat
  • produces dark pigment enzyme for fur colour
  • function at temperature less than body temperature
  • thus, lower temperature body parts are dark in colour
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5
Q

example of effect of pH to variation

A
  • hydrangea sp. plant
  • produces blue flower in acidic soil
  • pink in alkaline soil
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6
Q

example of effect of light to variation

A
  • alter skin colour
  • ultraviolet ray destroy melanin pigment of exposed skin
  • more melanin pigment produced
  • cause skin to be darker
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7
Q

how crossing over affect the variation

A
  • occurs between non-sister chromatids of homologous chromosomes during prophase 1 of meiosis
  • produce new combination of genes
  • form gametes with different genetic materials
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8
Q

how independent assortment of chromosomes affect the variation

A
  • happen in metaphase 1 of meiosis
  • homologous chromosomes pair is arranged randomly on the equatorial plane
  • show two probabilities
  • different combinations of paternal and maternal chromosomes
  • different genetic content in gametes
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9
Q

how mutation affect the variation

A
  • permanent change occur spontaneously on genes or chromosome
  • create new genotypes
  • can be inherited if happen in gametes
  • cannot be inherited if happen in somatic cell
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10
Q

define variation

A

the difference in characteristics between a same population or species

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11
Q

what is natural selection

A

an evolutionary force that selects beneficial genes and removes the non-beneficial one.

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12
Q

3 necessity of variation

A
  • enables natural environment to continue selecting beneficial characteristics and remove the non-beneficial one
  • allows cross breeding among species to form new species
  • to ensure the survival of species when environment changes
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13
Q

explain continuous variation

A
  • difference in characteristics not distinct
  • graph: normal distribution//bell-shaped curve
  • quantitative, can be measured and graded
  • influenced by environmental factors
  • control by many genes
  • height, weight, skin colour
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14
Q

explain discontinuous variation

A
  • distinct differences in characteristics
  • graph: discrete distribution
  • no intermediate characteristics
  • qualitative, cannot be measured and graded
  • due to genetic factors
  • can be inherited
  • control by one genes, can be seen easily
  • fingerprint pattern, eye colour
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15
Q

why does someone has blue eyes

A
  • low level of melanin content in outer layer of iris
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16
Q

what is mutagen

A

the substance that causes mutation or increase the mutation rate to a dangerous level

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17
Q

what is mutant

A

the new genetic material produced by mutation

18
Q

3 types of mutagen

A
  • physical agents
  • chemical agents
  • biological agents
19
Q

2 physical agents cause mutation

A
  • ultraviolet from sun

- ionising rays (X-ray, alpha ray)

20
Q

4 chemical agents cause mutation

A
  • carcinogen
  • food preservations
  • formaldehyde
  • benzene
21
Q

2 biological agents cause mutation

A
  • virus

- bacteria

22
Q

how gene mutation occurs

A
  • known as point mutation
  • change in nucleotide base sequence of a gene
  • alter the genetic code to synthesise amino acid
  • change the protein structure
  • new protein form cannot function
23
Q

3 types of gene mutations

A
  • base substitution
  • base deletion
  • base insertion
24
Q

5 genetic diseases caused by gene mutation

A
  • thalassemia
  • cystic fibrosis
  • sickle cell anaemia
  • albinisme
  • haemophilia
25
what disease cause by base substitution
- sickle cell anaemia
26
what disease cause by base deletion
- cystic fibrosis
27
what disease cause by base insertion
- thalassemia
28
explain albinisme
- mutation of gene which responsible for producing the pigment of skin, hair and eyes - no pigment produced
29
explain sickle cell anaemia
- caused by the gene which responsible for synthesising of haemoglobin - crescent shape red blood cell
30
explain chromosomal mutation
- changes of chromosomal number or structure | - causes changes in characteristics
31
effect of changes in chromosomal structure
- changes in gene sequence in a chromosome - cause the abnormality to chromosome - knowns as chromosomal aberration
32
4 types of chromosomal aberration
- deletion - duplication - inversion - translocation
33
explain the changes in chromosomal number
- normal spindle fibers fail to form - homologous chromosome fail to separate during anaphase 1 in meiosis // - sister chromatids fail to separate during anaphase 2 in meiosis - caused a diploid organism to lose or gain more chromosomes - known as nondisjunction
34
what happen when YO zygote form
- the zygote die
35
characteristics of down syndrome
- slant eyes - flat nose - protruding tongue - broad forehead - mentally retarded
36
cause of Cri Du Chat syndrome
- partial deletion on the short arm of chromosome 5
37
characteristics of Cri Du Chat syndrome
- delay development in mental - physically retardation - most patient die during childhood
38
characteristic of Klinefelter syndrome
- 44+XXY - sterile male - long hands and legs - small testis - fail to produce sperms - voice and chest similar to women
39
characteristics of Jacob syndrome
- 44+XYY - male - taller than normal - pimples on face - slow acquiring speech - learning disability - weak muscle (hypotonia)
40
characteristics of Turner syndrome
- 44+XO - sterile female - lack of secondary female characteristics - undeveloped breast and ovaries - weblike neck - low IQ