c. diff

Question 1

c. diff risk factors

Answer 1

• > 65 yo
• GI surgery
• Tube feeding
• Immunocompromised
• Chemo
• Acid suppressing agents
• Abx

Question 2

High risk for c. diff treatment

Answer 2

Clinda, 3/4 cepg, quinolones

Question 3

Lower risk c. diff treatment

Answer 3

Erythromycin, amp/amox/pip-tazo, tetra

Question 4

Lowest risk c. diff treatment

Answer 4

Aminoglycosides, vanco, metronidazole

Question 5

Initial non severe c. diff

Answer 5

• WBC <15000 and SCr < 1.5

- Vanco, fidaxomicin, metronidazole

Question 6

Initial, severe c. diff

Answer 6

• WBC >15000 or SCr >1.5

- Vanco, fidaxomicin

Question 7

Initial, severe, complicated c. diff

Answer 7

• Hypotension, shock, ileus, megacolon

- Vanco plus metronidazole if ileus present

Question 8

Mild water loss

Answer 8

• < 5% body wt lost
• alert, restless
• increased thirst
• moist to slightly dry mucus membranes
• normal/slightly decreased urinary output

Question 9

Moderate water loss

Answer 9

• 6-9% body wt lost
• lethargic, restless
• low volume: low BP, high HR
• dry mucus membranes
• delayed cap refill
• dark urine

-oral replacement therapy - hypotonic oral rehydration

Question 10

Severe water loss

Answer 10

• > 10% body wt lost
• drowsy, limp, LOC
• bradycardia
• cyanotic
• skin “tenting”
• no urine production

IV fluids