Buzzwords Flashcards

1
Q

Third person auditory hallucinations

A

Schizophrenia

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2
Q

Mesocortical dopamine hypoactivity

A

Negative and cognitive symptoms in schizophrenia

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3
Q

Subcortical dopamine hyperactivity

A

Psychosis

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4
Q

What are the dopamine pathways in the brain?

A

Tuberoinfundibular, nigrostriatal, subcortical and mesocortical

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5
Q

Tuberoinfundibular is concerned with

A

Prolactin

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6
Q

Nigrostriatal controls the

A

Extrapyramidal motor movements

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7
Q

Mesolimbic pathway is concerned with

A

Motivation and reward

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8
Q

What dopamine pathway is dysregulated in schizophrenia?

A

Mesolimbic

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9
Q

Mesolimbic Da blockade vs agonism

A

Depression

Psychosis

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10
Q

What atypical anti-psychotics causes the most weight gain?

A

Olazapine

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11
Q

Clozapine side effects

A

Agranulocytosis

Weight gain

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12
Q

How often do you monitor clozapine?

A

Once a week for first 6 months, once every 2 weeks for next 6, every 4 weeks after and every month after discontinuation

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13
Q

Brain changes in schizophrenia

A

Reduced frontal lobe volume, enlarged ventricles, reduced grey matter in temporal cortex

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14
Q

Pressure of thought is seen in

A

Mania and schizophrenia

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15
Q

Poverty of thought means that the patient reports

A

Lack/absence of thoughts

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16
Q

Thought blocking is what?

A

Abrupt and complete interruption of stream

17
Q

Thought blocking is associated with

A

Schizophrenia

18
Q

What do you treat EPSE with ?

A

Procyclidine

19
Q

Flight of ideas vs Knight’s move

A

Flight of ideas - link

Knight’s move - no link

20
Q

Amygdala is involved in

A

Normal response to threat

21
Q

What does the PFC do?

A

Dampen downs amygdala response to threat

22
Q

Management of OCD?

A

SSRI, SSRI, TCA or SSRI, SSRI or TCA (chlomipramine)

23
Q

Beck’s triad of psych

A

-ve feelings about self, world, and future

24
Q

NMDA antagonists produce

A

Psychotic symptoms

25
Q

What do you use in alcohol withdrawal ?

A

Chlordiazepoxide

26
Q

Alcohol withdrawal seizures within ____ hours

A

48

27
Q

Delirium tremes between ___ and ___ hours

A

48, 72

28
Q

Eosinophilic inclusions

A

Lewy bodies