Burkitt Flashcards

1
Q

Quais são as três variantes do linfoma de Burkitt?

A

Endêmico
Esporádico
HIV associado

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2
Q

Subtipo esporádico do linfoma de burkitt costuma cursar como clinicamente?

A

Massa abdominal
> ileocecal
> peritônio

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3
Q

Morfologia típica do Linfoma de Burkitt

A

Céu estrelado

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4
Q

Imunofenótipo do linfoma de Burkitt

A

CD19, CD20, CD10, PAX5, BCL6, CD79A > positivos
CD5, BCL2 e TDT negativos

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5
Q

Alteração molecular mais comum do linfoma de Burkitt

A

Translocação do MYC
t (8,14) IgH 70/80%

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6
Q

IPI Burkitt

A

Envolvimento SNC
LDH > 3x limite superior
>= 40 anos
PS >= 2

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