Bugs - Pseudomonas and ICU related Flashcards
diagnostic microbiological charasteristics of pseudomonas
non-lactose fermenting
oxidase positive
aerobic GN rod
smells like grapes
where does pseudomonas hang out?
who gets these infecitons?
loves wet places/fluids!
its ubiquitious in community and hospital
poeple w/compomised host defenses, disturbed barriers(burns, catheters, etc), and CF pts
most clinically relevant pseudomonas species?
pseudomonas aeruginosa
virulence factors for pseudomonas?
- pili, flagella for adherence/movement
- LPS(endotoxin)
- polysaccharide capsule(slime coat)
- Exotoxin A(ETA): similar to diptheria toxin; causes necrosis
- T3S: exoenzyme S, secreted toxins
- degradative enzymes
fevers, chills, purulent sputum, dyspnea
what pseudomonas syndrome does this describe
pneumonia caused by pseudomonas
ecthyma gangrenosum can result from what manifestation of a pseudomnas infection?
ecthyma gangrenosum is a buzzword for pseudomonas
**pseudomonal bacteremia secondary to pneumonia or other infection **can cause this ischemic necrotic ulceration w/raised violaceous margins
most common bacterial infection of burn pts?
pseudomonas!
hot tub folliculitis
low grade fever, self-limited, benign tender pruritic papules from infected water source
caused by pseudomonas
pseudomonas manifestation in ear is called?
swimmer’s ear/otitis externa; gross, pus exudates; its just gross;
what drugs cover pseudomonas
pip/tazo
cefepime
ceftazadime
aminoglycosides
imipenem
meropenem
fluoroquinolones(ciprofloxacin)
aztreonam
polymyxins
describe the microbiological characteristics of acinetobacter
GN coccobacillus
non-lactose fermenter; oxidase NEGATIVE
aerobic and non-motile
most clinically relevant acinetobacter spp?
acinetobacter baumannii
where is acinetobacter found?
where do infections usually occur?
found in water/soil; colonizes skin, respiratory tract, GI tract
primarily a nosocomial pathogen, particularly ICU
what disease does acinetobacter causeusually?
similar to pseudo:
catheter associated UTI(CAUTI)
ventilator associated pneumonia(VAP)
central line associated blood stream infeciton(CLABSI)
- s. maltophila*
- b. cepacia*
full names?
where are these guys contracted?
- stenotrophomonas maltophila*
- burkhoderia cepacia*
more ICU bugs
treat steno w/TMP-SMX
