Buffer System Flashcards

1
Q

Water molecules forms dipole.

T/F

A

T

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2
Q

Water molecules forms hydrogen bonds.

T/F

A

T

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3
Q

the molar concentration of H+ ions (or of OH− ions) in pure water is the product of the probability, ______ , times the _________

The result is ________ mol/L.

A

1.8 ×10−9

molar concentration of water, 55.56 mol/L.

1.0×10−7

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4
Q

pH IS THE ________ OF THE ______

A

NEGATIVE LOG

HYDROGEN ION CONCENTRATION

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5
Q

The term pH was introduced in ____ by _______ , who defined pH as the negative log of the hydrogen ion concentration:

Mathematically,
pH = __________

A

1909

Sörensen

˗ log [H+]

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6
Q

For example, for pure water at 250C,

 ˗ log [H+] =  ˗ log [\_\_\_] = - [\_\_\_] =\_\_\_
A

10-7

-7

7

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7
Q

Acids are proton _____ and bases are proton ____.

A

donors

acceptors

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8
Q

Strong acids (eg, HCl or H2SO4) (completely or partially?) dissociate into ____ and ____ even in strongly acidic solutions (low pH).

Weak acids dissociate (completely or partially?) in acidic solutions.

strong bases (eg, KOH or NaOH) are (completely or partially?) dissociated at high pH.

A

Completely

anions and cations

Partially

Completely

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9
Q

Milk is acidic

T/F

A

F

Slightly acidic

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10
Q

Henderson-Hasselbalch equation,

???

A

Ph = pka + log(salt / acid)

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11
Q

Hasselbach equation

when the concentrations of base and acid are the same, then pH is ______.

Thus, when the acid is _______, pH and pKa have the same values.

A

equal to pKa

half ionized

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12
Q

Buffers are solutions which can _______ in pH when ______ is added.

A

resist changes

acid or alkali

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13
Q

Factors Affecting pH of a Buffer

The pH of a buffer solution is determined by two factors:

The value of pK: The lower the value of pK, the (lower or higher?) is the pH of the solution.

A

Lower

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14
Q

the buffer capacity is determined by the _________ of ______ present, as well as by their __

A

actual concentrations

salt and acid

ratio

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15
Q

Buffering capacity is the ____________ which is necessary for a change in pH of ____________ of buffer solution.

A

number of grams of strong acid or alkali

one unit of one liter

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16
Q

The buffering capacity of a buffer is defined as the ability of the buffer to resist changes in pH when an acid or base is added.

T/F

A

T

17
Q

Three major buffering systems

A

Protein buffering system

Hemoglobin buffer system

Carbonate acid- Bicarbonate

18
Q

Major buffers in the ICF

major buffers in the ECF

A

Phosphate buffer and protein buffer system

Carbonic acid bicarbonate and protein buffer system

19
Q

Protein buffering system

If pH climbs, the ____ group of amino acid acts as a _____

If the pH drops, the ____ group acts as a ____

A

carboxyl; weak acid

amino; weak base

20
Q

Hemoglobin buffer system

Prevents pH changes when PCO2 is rising or falling

T/F

A

T

21
Q

Carbonic acid-bicarbonate buffer system

Has the following limitations:

(Can or Cannot?) protect the ___ from ___ changes due to increased or depressed ___

Only functions when _______ and _______ are working normally

It is limited by availability of _____________

A

Cannot ; ECF; ph ; CO2 levels

respiratory system and control centers

bicarbonate ions (bicarbonate reserve)

22
Q

Maintenance of acid-base balance

Lungs help regulate pH through _________________ buffer system

Kidneys help regulate pH through _____

A

carbonic acid - bicarbonate

renal compensation