Buchele Endocarditis Flashcards
What causes acute infective endocarditis? Where does it develop?
S. aureus
Develops on normal heart valve endothelium
What causes subacute infective endocarditis? Where does it develop?
- S. viridans and Enterococcus
- Develops on damaged heart endothelium
What is Marantic endocarditis, who is it seen in, and how is it found? (aka non bacterial thrombotic endocarditis)
- Develop on sterile platelet vegetations on cardiac valves
- Seen in patients with a metastatic malignancy
- Found on autopsy
What is Libman-Sacks endocarditis? Wo does it present in?
- Seen in patients with lupus
- sterile platelet vegetations on cardiac valves
How do those with Marantic and Libman Sacks endocarditis present?
- New cardiac murmur in setting of an embolic disease
Who does infective endocarditis effect?
- Older than 60
- Males
- IV drug use
- Poor dentition
- Structural heart disease
- Implanted cardiac device
How will an IV drug user with endocarditis present?
With right sided endocarditis due to S.aureus
What are the most common 3 pathogens of endocarditis?
- S. aureus
- S. viridans
- Enterococci
If you have a patient who has IE due to streptococcus bovis, what should you look for?
- Colon cancer or IBD
What are HACEK?
- Fastidious gram negative bacilli
- Haemophihlus
- Actinobacillus
- Cardiobacterium
- Eiknella
- Kingella
How will a patient with Infective endocarditis present?
- Fever >38
- Anorexia, weight loss, night sweats
- New cardiac murmur (usually regurgitation)
- Vascular embolic events
- Rarely:
- Oslers nodes
- Janeway lesions
- Roth spots
- Splinter hemorrhages
What are osler’s nodes?
Red raised painful lesions in distal extremeties
what is the modified duke criteria for diagnosing IE?
- Echocardiography
- Blood cultures (before abx)
clinical diagnosis of IE?
(dont need to memorize?)
- Major:
- positive blood culture
- persistent positive blood culture
- evidence of endocardial involvement via echo
- new regurgitation
- Minor:
- predisposition
- fever
- vascular phenomenon
- immunological phenomenon
- micro evidence
Cardiac complications of IE?
- HF
- Perivalvular disease
- Pericarditis