Bubonic plague Flashcards

exam 1

1
Q

what is the causative agent of the plague

A

gram-negative bacterium Yersinia pestis

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2
Q

transmission of plague

A

getting bit by fleas who ate infected animals
eating infected animals
direct contact w infected persons/animals

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3
Q

incubation period

A

1-6 days

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4
Q

symptoms of bubonic

A

rapid onset of fever, painful swollen lymph nodes,

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5
Q

symptoms of pneumonic

A

high fever, pneumonia, cough, bloody sputum, chills

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6
Q

symptoms of septicemic

A

fever, prostration, hemorrhagic or thrombotic phenomena, progressing to necrosis

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7
Q

what is the deadliest plague

A

pneumonic

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8
Q

death rates of plagues of left untreated

A

30-60 % : bubonic
100% fr both pneumonic and septicemic

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9
Q

diagnostic sample of the plague

A

isolation of bacteria from bubo aspirates, blood cultures or sputum cultures

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10
Q

identification of plague

A

cultures
serologic test for Y pestis f1 antigen

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11
Q

antibiotics of the plague

A

gentamicin
doxycycline
ciprofloxacin
levofloxacin

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12
Q

vaccines for plague

A

killed whole cell vaccine
live attenuated vaccine
subunit vaccine
monoclonal antibodies

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