bri thinks important Flashcards
CYP inhibitors
CRACK AMIGOS Ciprofloxacin Ritonavir Amiodorone Cimetidine Ketoconazole Acute alch use Macrolides Isoniazid Grapefruit juice Omeprazole Sulfonamide
CYP inducers
Guinness, Corona, PBCS Chronic Alchism Griseofulvin Carbamazepine Phenytoin Benzos Rifampin St johns wort Chronic alchism
antedotes for
CO =
CO = SVxHR
fick principle =
rt O2 consumption / (arterial O2 content)(venous O2 content)
EF =
SV / EDV
MAP =
P = QxR
MAP = CO x resistance
=2/3diastolic + 1/3 systolic
pulse pressure =
systolic p - diastolic p
Downs synd
- symp
- increased risk for
- hormone levels in utero
- US
- d/t
- intellectual disability, flat facies, prominent epicanthial folds, simean crease
- duodenal atresia, endocardial cushio defects, ALL, AML, Alz, polycythemia
- decr AFP, incr bhcg, decr estriol, incr inhibin A
- US: nuchal translucency
- d/t maternal nondisjunction of homologs during anaphase of meiosis 1
Edwards synd
- which trisomy
- present
- hormones in utero
- 18
- intellectual disability, rocker bottom feet, micrognathia, clenched hands, prominent occiput
- decr bhcg, AFP, estriol, nml inhibin A
PAtau synd
- which trisomy
- present
- hormones in utero
- US
- 13
- intellectual disability, rocker bottom feet, microcephaly, cleft lip and palate, holoprosencephaly, polydactyly, congenital <3 dis
- decr bhcg and PAPP-A
- nuchal translucency
Ad dis’s
- ADPKD
- achondroplasia
- FAP
- gardner synd
- familial hypercholesterolemia
- hereditary hemorrhagiv telangiectaisa
- hereidtary spherocytosis
- HD
- marfans
- MENs
- NF1, 2
- Tuberous sclerosis
- vHL
trimuc reapeat dis’s
- fragile x synd
- friendrich ataxia
Renal clearance eqn and what substances used to estimate
= (U x V) / P
- U = urine conc
- V = urine flow rt
- p = plasma conc
inulin tells clearance, Cr is what we use to estimate
Renal plasma flow eqn and what we use to estimate
= (Upah x V) / Ppah
- v = urine flow rt
