Breast surgery Flashcards

1
Q

What is part of the breast triple assessment?

A

clinical assessment
imaging
+/- biopsy

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2
Q

If there is a scaly nipple, what should you suspect?

A

Paget’s disease of the breast

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3
Q

How does breast eczema usually present?

A

affects areola and usually spares nipple

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4
Q

If you suspect breast cancer in a patient <40, what imaging should be done?

A

ultrasound +/- core biopsy
mammogram if malignant

breasts are generally denser so mammogram less good in younger patients

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5
Q

If you suspect breast cancer in a patient <40, what imaging should be done?

A

mammogram + ultrasound +/- core biopsy

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6
Q

What is the number system used to assess breast cancer?

A

1 = normal
2 = benign
3 = indeterminate, probably benign
4 = suspicious for malignancy
5 = highly suspicious for cancer

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7
Q

What is the gold standard biopsy type for breast cancer?

A

core biopsy (not fine needle aspiration)

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8
Q

Describe cyclical breast pain

A

mild breast pain
<5 days before menstrual cycle
dull, aching or burning
no association with cancer
exacerbation of sx prior to menopause, most resolves

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9
Q

Describe non-cyclical breast pain

A

shorter pain
usually unilateral
exacerbations of pain for no clear reason and difficult to treat
generally not associated with cancer (0.4% is cancer)

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10
Q

What are some other origins of mastalgia?

A

scapular bursitis
costochondritis
lateral extramammary pain syndrome
cervical radiculopathy

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11
Q

Breast pain management

A

supportive bra, day and night
weight loss
caffeine reduction
medications - SSRI, OCP, HRT
topical NSAIDs
vitamin E supplements

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12
Q

Clear nipple discharge cause

A

intraductal papilloma

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13
Q

Milky nipple discharge causes

A

physiological up to 2 years after breastfeeding
prolactinoma

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14
Q

Purulent nipple discharge cause

A

periductal mastitis - antibiotics, drainage of collection, smoking cessation

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15
Q

Multi-coloured nipple discharge cause

A

duct ectasia - normal ageing of breast/ducts

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16
Q

Blood-stained nipple discharge causes

A

intraductal papilloma
malignancy

17
Q

Non-proliferative benign breast lesions

A

cysts
duct ectasia
fibroadenoma
lipoma

18
Q

Proliferative benign breast lesions

A

sclerosing adenosis
intraductal papillomas

19
Q

Breast cancer risk factors

A

age
gender
genetics/family history
oestrogen exposure (early menarche, late menopause, nulliparous, pregnancy age>35, not breastfeeding)
OCP - weak risk
HRT (beyond age 55, risk returns to normal 5 years after stopping)
previous benign breast disease
obesity
alcohol
previous radiation exposure (eg. mantle radiotherapy for lymphoma)

20
Q

Non-invasive breast cancer subtypes

A

ductal carcinoma in situ
lobular carcinoma in situ

21
Q

Invasive breast cancer subtypes

A

invasive ductal carcinoma
invasive lobular carcinoma
other types: tubular, micropapillary, apocrine, metaplastic

22
Q

What receptors are all breast tumours routinely screened for?

A

oestrogen receptor (ER)
progesterone receptor (PR)
HER2

23
Q

What breast cancer type has worst prognosis?

A

triple negative

24
Q

What genes are tested for in breast cancer?

A

BRCA1
BRCA2
PALB2
ATM
CHEK2

25
Q

Indications for genetic testing in patients without a personal history of breast cancer

A

1st degree relative with breast or serous ovarian cancer
AND
combined pathology-adjusted manchester score>20 or BOADICEA score >10%
AND
no living affected individual available for genetic testing
AND
no deceased affected individual with tissue available for testing

26
Q

Indications for genetic testing in patients with breast cancer

A

breast cancer <30y
bilateral breast cancer <50y
triple negative breast cancer <60y
male breast cancer
non-mucinous ovarian cancer
breast cancer and a 1st degree relative with breast cancer (both <45y)
ashkenazi jewish ancestry

27
Q

What risk-reducing strategies can be used for patients at high risk of breast cancer due to genetics? (eg. BRCA 1/2)

A

surgery - bilateral prophylactic mastectomy
risk-reducing salpingoophrectomy

chemoprevention - tamoxifen daily for 5y

28
Q

Who is offered a mammogram in NHS screening?

A

women aged 50 to 71 offered a mammogram every 3 years
women over 71 can request the screening continues if they wish