Breast CA Flashcards
1
Q
What were inclusion for Keynote 522 TNBC
A
- t2 or greater
- operable
TC pembro, AC pembro, surgery, pembro x9
2
Q
BRCA 1/2 most common in…
A
1 - TNBC
2- HR Positive
3
Q
Role for adjuvant capecitabine in TNBC?
A
6-8 cycles for Those without a path CR after surger
4
Q
Who goes to primary surgery with TNBC?
A
T1b, n0
Primary less than 1cm
5
Q
Neoadjuvant options for HER2+ breast CA
A
- TCHP
- AC/THP
6
Q
What patients get neoadjuvant tx for HR+ HER2- disease?
A
- bulky / non operable
- those strongly desiring breast conserving surgery
7
Q
N1/2/3 breast staging
A
1 - 1-3 nodes
2 - 4-9 nodes OR internal mammary node
3 a 10+ nodes OR ipsilateral Supra lab node
8
Q
Who gets adjuvant abemiciclib
A
High risk
-4+ nodes
- Ki67 20%
Primary >5cm
