Brain tumours Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Name the adult brain tumors

A
  • Glioblastoma Multiforme
  • Oligodendroglioma
  • Meningioma
  • Hemangioblastoma
  • Pituitary adenoma
  • Schwannoma
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2
Q

What adult tumour commonly crosses the midline?

A

Glioblastoma Multiforme

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3
Q

What tumor will have pseudopalisading tumor cells and will be GFAP +ve on histology?

A

Glioblastoma Multiforme

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4
Q

What are the features of glioblastoma multiforme (histology and on CT)?

A

Histology:
- Pseudopalisading tumor cells
- GFAP +ve

Grossly:
- Crossing midline + Malignant

GlioPlastoma Multiforme
- G: GFAP +ve
- P: Pseudopalisading cells
- M: Midline + Malignant

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5
Q

What tumor will have a ‘chicken wire capillary pattern’, ‘fried egg’ cells and calcified tumors?

A

Oligodendroglioma

OliEGGodendroglioma
- chicken-wire, fried egg cells, calcium

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6
Q

Why are Oligodendroglioma cells called fried egg cells, what is seen on histology?

A

Round nuclei with a clear cytoplasm

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7
Q

What will be seen on histology in meningioma?

A
  • Psammoma bodies and spindle cells
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8
Q

What meninges do menigiomas arise from?

A

Arachnoid

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9
Q

Where are meningiomas located?

A

Superficially

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10
Q

Are meningiomas benign or malignant?

A

Benign

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11
Q

Are glioblastoma multiforme benign or malignant?

A

Malignant

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12
Q

Oligodendroglioma benign or malignant?

A

Can be both

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13
Q

What are the features of meningiomas?

Also pneumonic:

A
  • Benign
  • Superficial
  • Arachnoid origin
  • Psammoma bodies and spindle cells on histology

MEN have problems with PSA
- Psamomma bodies
- Superficial, Spindle cells
- Arachnoid origin

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14
Q

What are the general and histological features of hemangioblastoma?

A
  • Blood vessel origin - EPO producing
  • Thin-walled capillaries on histology
  • Associated with Von Hippel Lindau (chr 3)
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15
Q

Where are Schwannomas located?

A

Cerebellopontine angle
- CN7 and 8

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16
Q

What will Schwannomas be +ve for on histology?

A

S-100

17
Q

What condition will those with bilateral schwannomas have?

A

neurofibromatosis type 2
- NF2

18
Q

What are the features of Schwannomas?

  • Pneumonic
A

SCHW-annoma
- S100 +ve
- Cerebellopontine angle
- Hearing (CN8)
- Winking (CN7)