Brain Flashcards

1
Q

Thalamus

A

gateway to cortex
all projecting neurons excitatory (glutamate)

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2
Q

Cortex cells

A

Has 6 layers
Pyramidal cells in all except II - excitatory (glutamate)
Stellate - level IV sensory input
Interneurons
Inhibitory interneurons (basket and chandelier) - GABA, terminate on pyramidal

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3
Q

Reticular formation

A

Related to level of arousal (RAS)
surrounds 4th vent and cerebral aqueduct
Cell bodies for Norad, seratonergic and cholinergic

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4
Q

Evoked cortical potential

A

primary - specific to locatin, first small positive and then negative
secondary - large positive, less specific

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5
Q

Brain waves

A

delta - 0-4 deep sleep dreamless
Theta - 4-8 REM deep meditation
Alpha - 8-13 awake and chilled
Beta - 13-30 awake concentrated
Gamma - >30 multi processing

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6
Q

Neurotransmitters and sleep

A

sleep brainstem (REM) - decreased norad and seratonin, more ACh
Hypothalamus - increased GABA, decreased histamine

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7
Q

Brain areas motor planning

A

primary motor - action
supplemetary motor - planning
premotor - posture

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8
Q

Corticospinal tract

A

Lateral - crosses medulla, fine motor control distal (80%)
Ventral - cross at level, proximal muscle posture (20%)

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9
Q

Corticobulbar tract

A

From motor cortex to motor neurons V, VII, XI through internal capsule
Controla movement head and neck
Pyramidal tract

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10
Q

Mid brain function

A

vision, hearing, temp, motor, sleep and arousal

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11
Q

Pons function

A

CN V-VIII
pneumotaxic
sensory to thalamus
signals from brain to cerebellum and medulla

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12
Q

medulla

A

autonomic function

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13
Q

Thalamus

A

sensory, motor and limbic system
LGN visual
MGN auditory

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14
Q

Cerebellar peduncles

A

superior - deep brainstem to red nucleus, brainstem and thalamus
Middle - afferent fibres from contralateral pontine nuclei
Inferior - afferent from BS and spinal cord, efferent to vestibular nuclei in medulla and pons

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15
Q

Brainstem

A

midbrain, pons, medulla

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16
Q

Cerebellar fibres

A

climbing - excitatory in deep, input from inf olivary proprioceptive, output to purkinje
mossy - from pontine lat retic nucleus to granular and golgi cells

both excitatory and proprioceptive climbing >mossy

17
Q

Divisions cerebellum

A

vestibulo (floculonodular) - equilibrium and eye movements
spino - smooth and coordinated movement
cerebro - with motor cortex for planning

18
Q

Parasymp nuclei

A

III - edinger westphal - ciliary ganglia
VII - sphenopalatine gang to lacrimal and nasal, submand gang to submand and subling glands
IX - otic ganglion to parotid
X
S2-4

19
Q

Atropine

A

anticholinergic
hot as a hare etc
tx physostigmine

20
Q

organophosphate

A

cholinergic
miosis, d andv, bronchoconstrict, brady
tx atropine, pralidoxime

21
Q

Sympathetic only innervatin

A

liver, adrenal medulla, adipose, sweat, kidney, vessels (para via NO)

22
Q

Hypothalamus functino

A

temp and chemical consistency
with limbic system for emotion
lateral to thalamus

23
Q

Post pituitary

A

ADH and oxytocin
from supraoptic and paraventricular nuclei hypothalamus
from magnocellular neurons

24
Q

Ant pituitary

A

FSH
LH
ACTH
TSH
Prolactin
GH

25
Thirst
osmoreceptors on ant hypothalamus t hypertonicity and barreeptors in cartotid sinus and artic arch to hypovolaemia to hypothalamus for thirst
26
Oxytocin
GPCR in breast and uterus Uterus receptos increase in late pregnancy Inhibited by progesterone Activated by oestrogen
27
Afferents temp to hypothalamus
20% each spinal cord deep tissue skin Brain hypothalamus
28
Fever how it happens
Edndotoxins release cytokines Activates preoptic hypothalamus which releases prostoglandins These cause raised temp (aspirin decreased temp by working on prostoglandins) Fever stops microorganism growth and helps antibody production
29
Explicit memory
Facts Semantic or episodic stored in medical temporal lobe and hippocampus
30
Implicit memory
primary - neocortex procedural - striatum asociative - amygdala and cerebellum non associative - multiple
31
Short vs long term memory
Short - hippocampus Working - central exec of prefrontal cortex, verbal and visiospatial input Long term - neocortex
32
Creating memory
hippocamus --> mamillary bodies in limbic system --> halamus (via mammillothalamic tract) --> prefrontal cortex --> basal forebrain --> cholinergic projections to neocortex (lost in alzheimers)
33
Decorticate and decerebrate
Decorticate gcs3 flexion rubrospinal, above red nucleus Decerebrate gcs2 reticilospinal