Bradykinin Flashcards
0
Q
Control of bradykinin action in asthma and COPD
A
Antimuscarinic drugs, Ipratropium bromide
NSAIDS
Corticosteroids limit PG and LT mediation of Proinflammatory respiratory sx
1
Q
Bradykinin
A
Bradykinin generated in pathophysiologic cond such as inflammation, trauma, burns, shock
B1 receptor: Proinflammatory (Neutrophil recruitment)
Tox: Pain, edema
B2 receptor: Bronchoconstriction, Vasodilation and vascular permeability
Tox: Asthma, COPD, inflammatory hyperemia, hypotension
