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Pharmacology > Bp > Flashcards

Bp Flashcards

0
Q

What can it cause

A

Stroke, heart disease, peripheral vascular disease

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1
Q

Hypertension figures

A

More than 140 systolic / 90 diastolic, 1 in 4 adults

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2
Q

Bp= … X …

A

Bp= CO X TPR

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3
Q

CO= … X …

A

CO= HR X SV

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4
Q

Initial treatment

A

Lifestyle change

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5
Q

Targets for hypertensives (4)

A

Kidney, heart, blood vessels, brain

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6
Q

A B C D

A

Ace inhibitors, beta blockers, calcium channel blockers, diuretics

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7
Q

Renin angio tensin system

A

Renin converts angiotensinogen to angio tensin I, ace enzyme converts it to angiotensin II which is active

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8
Q

What does angiotensin II do

A

Aldosterone to increase blood vol, vasoconstriction

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9
Q

Captopril

A

Ace inhibitors

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10
Q

Enalapril

A

Ace inhibitors

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11
Q

Trandolapril

A

Ace

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12
Q

Ramipril

A

Ace

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13
Q

Lisinopril

A

Ace

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14
Q

Action of ace inhibitors

A

Block the at 1 receptors so prevent angiotensin 1 being converted into angiotensin 2

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15
Q

Ace side effects

A

Dry cough in 10-20% of users

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16
Q

Losartan

A

Angiotensin receptor antagonist

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17
Q

Candesartan

A

Angiotensin receptor antagonist

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18
Q

Valsartan

A

Angiotensin receptor antagonist

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19
Q

Action of Angiotensin receptor antagonist

A

Block the receptors AT1 and cause vasodilation don’t cause the dry cough like normal ace

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20
Q

Action of beta blocker

A

Stop the response of NS on the heart by blocking the B1 receptors, reduce CO, reduce renin release and NS vasoconstriction

21
Q

Labetalol

A

Beta blocker

22
Q

Atenolol

A

Beta blocker

23
Q

Bisoprolol

A

Beta blocker

24
Q

Metoprolol

A

Beta blocker

25
Q

Propranolol

A

Beta blocker

26
Q

Sotalol

A

Beta blocker

27
Q

Side effects of beta blockers

A

Can be bad for asthma as can cause effect on B2 in the lungs

28
Q

Action of alpha blocker

A

Block action of adrenaline and nor adrenaline on blood vessels cause dilation

29
Q

Prazosin

A

Alpha blocker

30
Q

Doxazosin

A

Alpha blocker

31
Q

Terazosin

A

Alpha blocker

32
Q

Action of calcium channel blockers

A

Dilate arteries, reduce Herat contra tiling and reduce HR

33
Q

Nifedipine

A

Calcium channel blocker

34
Q

Amlodipine

A

Calcium channel blocker

35
Q

Nicardipine

A

Calcium channel blocker

36
Q

Verapamil and diltiazem

A

Calcium channel blocker DONT USE WITH beta blockers

37
Q

Interaction of Calcium channel blocker

A

Interact with grapefruit juice

38
Q

Action of thiazide diuretics

A

Increase urine output so decrease blood vol and bp, actin kidneys by stopping Na being pumped back in

39
Q

Indapamide,

A

Thiazide diuretics

40
Q

Chlortalidone

A

Thiazide diuretics

41
Q

Bendroflumethiazide

A

Thiazide diuretics

42
Q

Side effects of thiazides

A

Hypokalaemia, gout, erectile disfunction

43
Q

Amiloride and spironolactone

A

Potssium sparing diuretics

44
Q

Furosemide

A

Loop diuretic for extreme hypertension

45
Q

Drug therapy for hypertension

A

Less than 55. More than 55 or black
A or B. c or D.
A+C or A + D
A + C + D

46
Q

Ace results

A

Block renin angiotensin cycle

47
Q

B blocker result

A

Decrease HR, dilate arteries, reduce renin

48
Q

Calcium channel blockers result

A

Decrease HR, dilate arteries

49
Q

Diuretics results

A

Increase urine output thus reducing total blood volume

Pharmacology (9 decks)

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