Bovine TB Flashcards

1
Q

What Mycobacterium strains cause TB?

A
  • Avium
  • Tuberculosis
  • Bovis
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2
Q

What are the characteristic features of Mycobacterium bovis?

A
  • Aerophilic
  • Heat sensitive
  • Sensitive to bleach (1:9)
  • Slow growth rate
  • Obligatory hosts
  • Remain viable in cold conditions
  • Likes warm, moist, protected environments - stagnant water, faeces
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3
Q

Outline the pathogenesis of M. bovis.

A
  • Inhalation/ ingestion
  • Spread through lymphatic channels & haematogenously
  • Reaches lungs and reproduces in macrophages
  • Cause caseous necrosis
    • Bacteria stop growing and lesion calcifies (may reactivate if immunosupressed)
    • Lesion liquifies - spreads = death
    • Bacteria coughed up in sputum
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4
Q

What inhalation dose of M. bovis is required to cause infection?

A

1-3 bacilli

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5
Q

Outline the clinical signs associated with bTB.

A
  • Progressive wt loss
  • Chronic low moist cough
  • Anorexia
  • Pyrexia - fluctuates
  • Mastitis
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6
Q

What Ddx. should be explored with c/s of TB?

A
  • Pulmonary abscess
  • Pleurisy
  • Pericarditis
  • 2nd to traumatic reticulopericarditis
  • Contagious pleuropneumonia
  • Bovine Leukosis
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7
Q

Tubercle.

Describe

A
  • 1-2cm
  • White nodular lesion
  • Focal/multifocal
  • Within lymphnodes or organs (thorax, liver + others)
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8
Q

Miliary type lesions

A

Small, multifocal/ coelescing white nodules in pleura and thoracic cavity

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9
Q

Which group of people are considered at zoonotic risk from bTB?

A

Immunocompromised

Consuming unpasteurised milk

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10
Q

Why are badgers considered continuous shedders of bTB?

A

They have unencapsulated granulomatous lesions so shed regularly

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11
Q

In which species is TB a notifiable disease?

A

Cattle

Deer

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12
Q

Tuberculin test

A

A comparative intradermal cervical test - uses bovine and avium tuberculosis

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13
Q

After how long are tuberculin tests reassessed?

A

72 hrs

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14
Q

What three results are possible from the tuberculin test?

A
  1. Negative - no action taken if whole herd is clear
  2. Suspect/ inconclusive - B 2-4mm > A
    1. Euthanase
    2. Retest after 60 days
  3. Reactor - B>A 5mm
    1. Slaughter, isolate, PM, milk discard
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15
Q

Which types of herd are considered high public health risk?

A

Bottling unpasteurised milk

Supplying raw milk to manufacturers of unpasteurised dairy products

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16
Q

How often do high risk herds require testing?

A

Annually

17
Q

What cattle control measures should be employed if TB is confirmed in a herd?

A
  1. Remove infected animals
  2. Movement resitrictions
  3. Short interval testing
    1. Minimum 60 days
    2. 2 consecutive tests required
  4. Gamma interferon testing - earlier detection
  5. Cattle tracing
  6. Testing neighbouring farms