Bones Flashcards

1
Q

components of skeletal system

A

bone
cartilage
joints
ligament
connective tissue

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2
Q

function of skeletal system

A

support against gravity
leverage
protection
storage of calcium
blood cell production

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3
Q

types of bone

A

flat (2 layers of compact bone with dipole in middle)
long (leverage)
short (transfer forces)
irregular (multi purpose)
sutual (bone between skull bones)
sesamoid (small develop in tendons)

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4
Q

long bone features

A

Diaphysis (shaft) main long part of 2 dense bone layers surround bone cavity
epiphyses (ends) made of spongy / trabecular bone covered in articular cartilage

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5
Q

osteoclast crusher cell

A

dissolves old bone to be replaced

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6
Q

osteoblast

A

immature bone cell secreting matrix proteins to become mineralised

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7
Q

osteoid

A

matrix protein

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8
Q

osteocytes

A

mature bone cells maintaining matrix by branching through allowing Ca to travel

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9
Q

osteoclasts

A

multi nucleated cell secreting acid and enzymes to dissolve bone matrix

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10
Q

structure of compact bone

A

osteon (long cylinder)
central canal (tunnel for blood vessels)
lamellae (concentric layers of matrix)
lacunae

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11
Q

what causes the osteon to be strong

A

collagen fibres in different directions

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12
Q

features of trabecular bone (sponge)

A

no ostens
no canal as nutrients can diffuse in
trabeculae (branching network strong in directions)
red and yellow marrow (red=provides nutrients and forms rbc, yellow=stores fat)

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13
Q

bone vs forces

A

osteons = strength in long axis
trabecular - strength in range of directions as trabeculae align according to direction of loading

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14
Q

periosteum

A

membrane outside bone
-outer fibrous layer = collagen fibres

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15
Q

endosteum

A

membrane lining bone
inner cellular layer for metabolism and blood vessels

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16
Q

compact vs trabecular bone - structure

A

C=osteons, canal, concentric lamellae
T=network of cross bridges

17
Q

compact vs trabecular bone - location

A

C=shaft of long bone
T=inside short / flat bone and epiphyses of long

18
Q

compact vs trabecular bone - blood supply

A

C=through canal and perforating canal
T=via red bone marrow

19
Q

ossification

A

formation / conversion to bone

20
Q

intramembrane ossification

A

inside formation of flat bone

21
Q

endochondrial ossification

A

bone forming inside cartilage

22
Q

appositional bone growth

A

adding more bone to outside increasing width

23
Q

remodelling of trabecular bone

A

as forces apply it become denser and compact into compact bone

24
Q

1st stage of endochondrial ossification

A

chondrocytes in calcifying matrix enlarge and die

25
Q

2nd stage of endochondrial ossification

A

osteoblasts cover shaft in a thin layer of bone

26
Q

3rd stage of endochondrial ossification

A

blood vessels and osteoblasts penetrate to form a primary ossification centre

27
Q

4th stage of endochondrial ossification

A

primary ossification centre enlarges until meets with collar

28
Q

5th stage of endochondrial ossification

A

secondary ossification centre formed at epiphyses forming 3 bones

29
Q

growth in bone length

A

3 sections of bone connected by cartilage allows expansion and stopped by hormones and fusion of cartilage

30
Q

appositional bone growth

A

bone deposited by osteoblasts outside while inside resorbed by osteoclasts.

31
Q

bone remodelling

A

continuous growth and breakdown
osteocytes detect forces and adapt to loading

32
Q

stage 1 of fracture repair

A

bleeding and formation of a clot to hold together bone

33
Q

stage 2 of fracture repair

A

formation of external callus (cartilage) and internal callus (sponge bone)

34
Q

stage 3 of fracture repair

A

external callus replaced by bone, internal unites broken ends

35
Q

stage 4 of fracture repair

A

initial swelling remodelled