Bone tumours Flashcards
What is the most common benign bone tumour
Osteochondroma
Osteochondroma - pathology
Bony outgrowth
Covered by cartilaginous cap
Osteochondrma - location
Around epiphysis of long bones
eg Knee
All osteochondromas remain completely benign. True or false?
False
- small malignant potential
Enchondroma - location
Intramedullary
Metaphyseal
Hands and feet
Enchondroma - pathology
Lucent (glowing) but has patchy sclerotic appearance
Enchondroma is usually asymptomatic. True or false?
True
Simple bone cyst - cause
Growth defect
Simple bone cyst - pathology
Single cavity of benign fluid filled cyst
Simple bone cyst - location
Long bones
Giant cell tumour - X-ray appearance
Soap bubble
Fibrous dysplasia - who gets it
adolescents
Fibrous dysplasia - location
Head and neck
Osteoid osteoma - pathology
Halo appearance
Osteoid osteoma - clinical features
Intense constant pain
Worst at night
Osteoid osteoma - management
NSAIDs
Common sites of bony metastasis?
Breast Prostate Lung Renal Thyroid
Malignant primary bone tumours are more common in younger/older age groups?
Younger
What is the most common malignant bone tumour?
Osteosarcoma
Osteosarcoma is more common in old people. True or false?
False
- young people
Osteosarcoma - location
Around the knee
Osteosarcoma - definition
Malignant tumour which produces bone
Osteosarcoma - genetics
Rb gene
Osteosarcoma is untreatable. true or false?
False
Chondrosarcoma - location
Pelvis
Chondrosarcoma - age
Older
Chondrosarcoma has fast metastatic potential?
False
- slow metastatic potential
Chondrosarcoma is untreatable. True or false?
True
Ewings sarcoma - who gets it
Adolescents
Ewings sarcoma - location
Long bones
Which malignant bone tumour has an onion skin appearance?
Ewings sarcoma
Ewings sarcoma - genetics
chromosome 22
Ewings sarcoma can commonly be confused with osteomyelitis. Why?
Raised inflammatory markers
Ewings sarcoma - biopsy appearance
Small round blue tumours
- due to high N:C ratio
What is different about prostate metastasis ?
Sclerotic metastasis
Rhabdomyoma
Tumour of skeletal muscle
Leiomyoma
Smooth muscle tumour
Schwannoma
Tumour of nerves
Haemangioma
Tumour of blood vessels
Where does angiolipoma usually occur?
Forearm
Angiolipoma is painful/painless
Painful
Which tumour is most common to occur as a complication of previous radiotherapy?
Angiosarcoma