Bone & Joint infection

Question 1

most common cause of osteomyelitis?

Answer 1

Staph A.

Question 2

3 types of osteomyelitis and most common cause for each

Answer 2

Hematogenous - sceptcaemia.
Direct Non-Haem - Trauma/Surg
Non-haem (local invasion) - pressure ulcer

Question 3

pathogenisis of haem osteomyeltitis (5)

Answer 3

1. slow flow through looped capillaries and venous sinusoids.
2. Bacteria seed in metaphyseal-epiphyseal junction
3. Poor penetration of WBCs
4. Pressure from pus further limits blood supply
5. infection spreads to subperiosteal space ( can invade shaft)

Question 4

what is different in terms of infection position in regards to infants?

Answer 4

infection can cross growth plate to invade epiphysis and joint

Question 5

2nd most common gram positive cause of bone infection?

Answer 5

Strep P

Question 6

most common gram neg cause

Answer 6

Would be H. Influenza Type B but coz immunized Kingella and salmonella

Question 7

most common bones of infection and why?

Answer 7

femur, tibia and humerus coz fastest growing?

Question 8

epidemiology of bone infection

Answer 8

most common in under 5

Question 9

treatment for uncomplicated osteomyeltisis

Answer 9

3-5 days IV Flucloxacillin then 3 week oral at home

Question 10

why is H. Influenza type B infection possible in infants

Answer 10

not fully immunized