Bone Flashcards
Identify 1-3.
- compact bone
- periosteum
- spongy bone (diploe)
large multinucleated motile cells, remove/resorb bone, forms from fusion of many monocytes, secrete enzymes that degrade bone, have ruffled border
osteoclast
Identify 1-3.
- epiphysis
- metaphysis
- diaphysis
these cells are responsible for secretion of organic component of bone, important for signaling for calcification of bone, found on surface of bone matrix, lots of RER
osteoblasts
part of osteon that contains vasculature
central canal aka Havershon’s canal
Identify.
cement line
fills in spaces between osteons, made of remnants of old osteons
interstitial lamellae
Identify what is marked with *
inner circumferential lamellae
This type of bone does not contain osteons.
spongy/trabecular bone
Identify.
osteons
where is spongy bone laid down?
along stress lines, found more internally in a bone
osteoblasts produce ___, the organic portion of ECM made up of type 1 collagen
osteoid
type of collagen present in lamellae of osteon?
how is it arranged?
type 1
run parallel to each other, at angle (next lamellae fibers run at 90 degree angle to previous lamellae fibers)
Identify 1-5.
- adipocytes
- osteocyte
- endosteum
- periosteum
- muscle
covers the outer surface of the bone, is vascularized, contains osteoprogenitor cells.
periosteum
long axis of bone- contains medullary cavity in center, has compact bone on outside
diaphysis (aka shaft)
___ lay down bone ____ break down bone
osteoblasts osteoclasts
main difference between woven & lamellar bone?
woven bone has collagen fibers in random directions, lower mineral content, more osteocytes
lamellar bone is collagen fibers parallel in rings, is well-organized, fewer osteocytes
Type of bone?
- woven bone
- lamellar bone
outer limit of each osteon, where it is very collagen rich
cement line
these cells are mesenchymal stem cells that can differentiate into osteoblasts, found in periosteum & endosteum
osteogenic cell
consists of cells that belong to stroma of marrow, main source of lining cells of haversian canals
endosteum
these sit in lacuna between lamellae of osteon
osteocytes
bone spicules present in spongy bone
trabeculae
cortical bone = ____ trabecular bone = ____
compact bone spongy bone
Identify 1-3.
- Haversian canal (central canal)
- Volkmann’s canal
- Sharpey’s fibers
Type of bone?
woven
this area of osteoclast helps prevent H ions from ruffle border from leaking out
sealing zone
where do osteoblasts sit in trabeculae?
along outside
these perforate the periosteum to supply the compact bone of a long bone
Sharpey’s fibers
type of cartilage found on ends of long bone
hyaline
Type of bone?
lamellar bone
Identify 1-2.
- cannaliculi
- osteocytes (in lacunae)
connect central canal of osteon to endosteum and periosteum
Volkmann’s canals
this area of long bone lengthens as you grow (separates the metaphysis & epiphysis)
epiphyseal plate
this lines the trabecullae of inner bone
endosteum
Type of bone?
woven/immature
functions of bone?
protection support mechanical basis for movement storage blood cell formation
end part of long bone
epiphysis
fibrous outer layer of periosteum is where ___ attachment occurs
muscle
flared out portion between diaphysis & epiphysis
metaphysis
direction of movement of nutrients in a trabeculae?
from outside to inside
these cells are totally surrounded by ECM, stuck in lacuna, cytoplastmic extensions for communication and nutrient passage, maintains the bone tissue that is present
osteocyte
Identify.
epiphyseal line
primary bone tissue is ____
secondary bone tissue is ____
woven bone (immature bone)
lamellar bone (mature bone)
Type of bone in 1-2?
- Compact bone (cortical bone)
- Spongy bone (cancellous bone)
Type of bone?
lamellar
shapes of bone?
long (shaft w/ 2 ends) short (cubed bones- ie tarsal, carpal bones) flat (ie skull, scapula) irregular (ie vertebrae) sesamoid (found in tendons ie patella)
Identify 1-3.
- Havershon’s canal (central canal)
- Lamellae
- Interstitial lamellae
Identify 1-2.
- osteoblast
- osteocyte
Indentify what is marked with *
What is arrow pointing to?
Outer circumferential lamellae
Periosteum
these cells can give rise to both osteoblasts & osteoclasts
osteogenic cells
part of osteon that surrounds central canal- concentric rings of bone matrix
lamellae
Spongy bone is a type of ___ bone
lamellar (secondary)
structural unit of compact bone
osteon
Identify cell type.
osteoclast
Identify 1-3.
- Osteoblasts
- Osteons
- Havershon’s Canal (central canal)
extensions of osteocytes used for nutrient transfer are called…
cannaliculi
the inorganic portion of ECM that gives the bone its hardness is ____
hydroxyapetite crystals
toward end of puberty, hyaline cartilage disappears and is replaced with bone, so you are left with remnant called…
epiphyseal line
these connect 1 cannaliculi to the next to pass nutrients
gap junctions
2 main components of hydroxyapetite crystals
Ca & P
Identify cell type.
osteoclast
boundary between __ &___ is where marrow cavity begins in a long bone
metaphysis & diaphysis
Identify 1-2.
- osteoblast
- osteoclast
Identify 1-2.
- Osteoblast (lots of RER)
- osteoid
Identify 1-5.
- interstitial lamellae
- outer circumferential lamellae
- Volkmann’s canal
- osteon
- central canal/ Havershon’s canal
these lamellae go around the whole outside surface
outer circumferential lamellae
