Bohr Effect on Oxygen Delivery to Tissue

Question 1

What shifts curve to the right

Answer 1

Increase temp (feer or exeercise), increase DPG (chronic lung dz), increase PCO2, decreased pH

MEans that less oxygen bound at same oxygen pressure as before

Question 2

Bohr effect with normal physiology

Answer 2

The venous pCO2 is higher than the arterial CO2…this means that the curve is shifted to the right

This means there is an increase in O2 delivered to cells due to the Bohr effect

Can also use graph to see total amount of O2 delivered

Question 3

During exercise

Answer 3

The PCO2 is even higher AND the O2 concentration is lower (in venous) so the difference in the amount of oxygen delivered is even higher

Question 4

Summarize Bohr effect

Answer 4

Facilitates O2 uptake in the lavolar capillaries and the O2 delivery in the peripheral tissue capillaries

Effect is more pronounced during exercise and in patients with lung dzs