Body Systems and Related Laboratory Tests Flashcards
function of integumentaery system
provides protection, regulates temperature,
and prevents water loss, converts the substance
7-dehydrocholesterol to vitamin D, sensory perception
viruses that affect integumentary system
rubella, rubeola,
and herpes zoster, which causes chickenpox and
shingles
skin cancer that affect integumentary system
squamous
cell carcinoma, basal cell carcinoma, and melanoma
What is antibody titers
Measures level of antibodies to specific
antigens. Commonly used to determine
whether a patient has (or has had in the past)
certain diseases
What do antibody titers test
Rubella, rubeola, chickenpox, shingles,
systemic lupus erythematosus (SLE); also
used to check for immune deficiencies and
autoimmune disease
immunoglobulin levels
Measures immunoglobulin levels; high level of
immunoglobulin A (IgA) or E (IgE) indicates an
allergic response
ig levels test for what?
Seasonal allergies, immunodeficiencies
what is wet prep and what does it test for?
- Microscopic evaluation of skin or nail scraping
- Fungal infections of the skin or nails
what is culture of scraping + what does it test for?
Skin scraping is placed in or on a culture
medium that supports the growth of
microorganisms. The microorganisms that
grow are then examined under a microscope to
diagnose infections caused by Staphylococcus
aureus and other bacterial, fungal, and parasitic
infections
- tests for Staph infection, athletes foot, ringworm, fingernal/toenail infection
what is skin biopsy + what does it test for
- Small piece of skin tissue is removed and
examined under a microscope - skin cancer
urine melanin
Urine is tested for level of melanin, a skin
pigment that may be found in urine if melanoma
is present
- melanoma
What do diseases and disorders that affect hte skeletal system include?
osteoporosis,
osteoarthritis and rheumatoid arthritis, gout, osteosarcoma (bone cancer),
and various disorders related to nutritional deficiencies or poor postur
what is Alkaline
phosphatase (ALP)
- tests for abn levels of ALp in blood
- tests for Bone tumors, Paget’s disease (abnormal
bone enlargement and deformation)
What is Calcium Ca
- abn calcium levels
- Rickets (children) or osteomalacia (adults);
these diseases involve softening of the
bones and serum calcium levels tend to
be decreased; increased calcium can be
seen in skeletal immobilization
What is ESR?
- Measures the rate at which erythrocytes settle at the
bottom of a calibrated tube; elevated levels indicate
the presence of inflammation - Some types of arthritis, including
rheumatoid arthritis
What is phosphourous
Measures phosphorus levels in serum, which contains
only 15% of the body’s phosphorus; the majority (85%)
is stored in the bones
- Gastrointestinal problems, malabsorption
What is Rheumatoid
factor (RF)
Tests for the autoantibody that is present in
rheumatoid arthritis
- Rheumatoid arthritis (but not juvenile-type
rheumatoid arthritis)
What is uric acid
Measures the level of uric acid in the blood to determine
whether the body is breaking it down properly
- Gout (a type of arthritis in which the body
does not break down uric acid adequately)
What is vitamin D
- Screens for abnormal levels of vitamin D
- Bone weakness or malformation or
abnormal metabolism of calcium
bone marrow biopsy
A needle biopsy to remove bone marrow for
diagnostic tests
- Multiple myeloma (cancer that starts in
bone marrow)
What is synovial fluid analysis?
Battery of tests that includes visual analysis;
microscopic analysis; measurement of glucose
proteins, LDH, and uric acid; and bacterial culture
- Gout, other types of arthritis, joint infections
what is Urine uric acid
- Screens for excessive uric acid in urine collected over
a 24-hour period - gout
What is torticollis?
- wry neck
aldolase
- blood levels of aldolase (glycolysis)
- Muscular dystrophy, muscle cell damage,
and infections in muscle tissue
autoimmune antibodies (muscular)
- Screens for abnormal antibody levels that
may indicate various autoimmune diseases - Myasthenia gravis, polymyalgia rheumatica,
lupus erythematosis
creatine kinase (CK)
Measures the level of the enzyme creatine
kinase in the blood; CK-MM is specific to
skeletal muscle damage, while CK-MB will
also be affected by skeletal muscle disorders
General muscle damage, muscular
dystrophy, skeletal muscle disease, muscle
damage due to myocardial infarction (heart
attack)
Lactate/lactic acid
Monitors production of lactic acid during
muscle activity or due to certain medications
heart failure
what is Lactate
dehydrogenase
(LH/LDH)
Measures the level of the protein LDH in the
blood; often performed when tissue damage
is suspected
Muscle injury, muscular dystrophy, blood
flow deficiency (ischemia)
Magnesium (Mg) (musuclar)
- amt of magnesium in blood
- Magnesium intoxication; high levels can
depress the neuromuscular system;
low levels can lead to neuromuscular
hyperexcitability, tetany, and seizures
myoglobin (muscle)
- amt of protein myoglobin in blood (myoglobin released in bloodstream when muscle tissue is damaged)
- Skeletal muscle inflammation or trauma,
myocardial infarction, muscular dystrophy,
rhabdomyolysis
Muscle biopsy
Trichinosis, toxoplasmosis, or other muscle
infections; muscular dystrophy; muscle
atrophy or necrosis (tissue death); polymyositis
urine myoglobin
Skeletal muscle inflammation or trauma,
myocardial infarction, muscular dystrophy,
rhabdomyolysis (breakdown of muscle fibers)
what is the most abundant ig?
IgG
what is IgM
s found in the lymph fluid and blood
and is the first antibody produced when exposure to a particular disease occurs
Antinuclear antibody
panel (ANA)
- Measures levels of the antibodies produced by the
immune system that attack body tissues - Rheumatoid arthritis, systemic
lupus erythematosus, scleroderma,
thyroid disease - specifically SLE (phleb essentials)
What is crp
- tissue necrosis
- Infections, rheumatic fever,
rheumatoid arthritis
monospot
- mononucelousis 2 antibodies
lymph node biopsy
- cancer sarcoidosis, tuberculosis
lymphatic fluid culture
various bacterial infections
internal respiration
gas exchange between the blood and body
cells
external respiration
exchange of air between the lungs (pulm/o,
pulmon/o) and the outside environment
respiratory acidosis
If the lungs
do not adequately remove CO2 from the blood, the increase in CO2 level
makes the blood more acidic (a lower pH)
respiratory alkalosis
relatively
higher levels of O2, the blood becomes more alkaline (a higher pH) (hyperventilation)
ABG
Measures levels of oxygen, carbon dioxide, and
bicarbonate (HCO3) as well as the pH (acidity or
alkalinity) in arterial blood
- Respiratory acidosis, respiratory alkalosis,
emphysema, chronic obstructive
pulmonary disease (COPD)
DNA study - respitory
CF
Electrolytes (Na, K,
Cl, CO2
Measures blood levels of sodium, potassium,
chloride, and carbon dioxide (in the form of bicarbonate [CHO3−])
- Cushing’s syndrome, COPD, and
acute disorders such as ketoacidosis,
methanol poisoning, or aspirin overdose
Bronchial washing
The patient’s respiratory tract is flushed with
a saline solution, which is then analyzed and
examined under a microscope for the presence of
foreign particles
Asbestosis and other environmentrelated respiratory disorders; lung cancer
Nasopharyngeal
specimens
Nasopharyngeal swabs are tested using DNA
probes to detect various viral infections
Influenza, H1N1, RSVa, RSVb
Sputum culture
Secretions from the lungs and bronchi are placed
on a culture medium; any microbial growth is
examined microscopically; often includes sensitivity
testing (culture and sensitivity or C&S) to determine
effectiveness of various antibiotics
Bronchitis, lung abscess, pneumonia,
tuberculosis
Throat culture
Material swabbed from the back of the patient’s
throat is placed on a culture medium; any microbial
growth is examined microscopically; often includes
sensitivity testing
Various bacterial infections, including strep
albumin and gi
Malnutrition, malabsorption, chronic
inflammatory diseases, chronic liver disease
aldolase and gi
Chronic hepatitis, obstructive jaundice
Alkaline phosphatase (ALP) and gi
Biliary cirrhosis, bile duct obstruction, liver
disease
amonia
Measures ammonia buildup in the blood Hepatic encephalopathy
Amylase
Measures the amount of the enzyme amylase
in the blood
Pancreatic disorders, perforated bowel
Carcinoembryonic
antigen (CEA)
Detects CEA in the blood; CEA is an antigen
that is found in the blood when certain types
of cancers are present
Intestinal, pancreatic, thyroid, lung, and
breast cancer, as well as cancers of the
reproductive and urinary tracts
Carotene
Determines the level of carotene in the blood Vitamin A deficiency
Glucose
Measures the amount of glucose (sugar) in
the blood
Type 2 diabetes, overactive or underactive
thyroid gland, pancreatic cancer, pancreatitis
Glucose tolerance test
(GTT)
Measures the amount of glucose (sugar) in
the blood over a specific length of time after
ingestion of a specific dose of glucose
Type 2 diabetes, gestational diabetes,
Cushing’s syndrome
Lipase
Measures the amount of the enzyme lipase in
the blood
Pancreatic disorders
Magnesium (Mg) gi
Malnutrition, malabsorption, alcoholism,
diabetic acidosis
Methylenetetrahydrofolate
reductase (MTHFR) test
Detects genetic mutation of the MTHFR gene Enzyme deficiency, causing poor folate
metabolism
Nutritional analysis
Measures the blood levels of various vitamins Malnutrition, nutritional imbalance or
deficiency
Potassium (K)
Measures the amount of potassium in the
blood
Cushing’s syndrome, gastrointestinal
disorders
Triglycerides
Measures the blood level of triglycerides Decreased in malnutrition, malabsorption;
increased in glycogen storage disease, highcarbohydrate diets, uncontrolled diabetes
Vitamins
Measures the levels of various vitamins
(A, B, C, etc.) in the blood
Malnutrition, malabsorption, nutritional
imbalance related to specific enzyme
deficiencies
Zinc
Measures the blood level of zinc Deficiency can cause stunted growth,
diarrhea, increased infections
Fecal fat
Measures amount of fat in the feces to
determine how well fat is being absorbed by
the body
Pancreatitis, gallstones, Crohn’s disease,
pancreatic cancer, celiac disease
Fecal occult blood
Determines whether blood is present in
the stool
Colon cancer, other gastrointestinal
cancers, esophagitis, gastritis,
hemorrhoids, inflammatory bowel disease
fecal white blood cells
Checks for white blood cells in the feces to
help determine the cause of inflammatory
diarrhea
Ulcerative colitis, salmonellosis, shigellosis
Gastric fluid analysis
Determines the pH and content of residual
gastric fluid in the stomach
Gastric ulcer, gastric cancer, tuberculosis,
pernicious anemia
Peritoneal fluid analysis
Examines fluid taken from the abdominal cavity
(peritoneal space) for presence of albumin,
protein, and red and white blood cells
Peritonitis, cirrhosis of the liver, lymphoma,
other gastrointestinal cancers
Stool culture
Stool sample is placed on culture medium; any
microbial growth is examined microscopically
Bacterial gastroenteritis, infections caused
by E. coli, C. difficile, and other bacteria
Stool for ova and parasites
(O&P)
Stool specimen is examined microscopically
to determine whether certain parasites or
their ova (eggs) are present
Amebiasis, giardiasis, and other parasitic
infections
Urine chemistries
Measure levels of glucose, ketones, protein,
and other chemicals in the urine
Gastrointestinal infections, type 1
diabetes, anorexia, malnutrition,
hyperthyroidism
Acetylcholine receptor
antibody
Determines presence or absence of
acetylcholine receptor antibody
Myasthenia gravis
Creatine kinase brain/smooth
muscle isoenzyme (CK-BB)
Measures the level of the creatine kinase BB
isoenzyme in the blood
Cerebrovascular accident (CVA,
stroke), lung cancer
Drug levels
Measures the blood levels of various therapeutic
drugs to monitor patient response and to help
determine therapeutic levels
Epilepsy, other brain disorders
Zinc
Measures the blood level of zinc Mental confusion, depression