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BM2 RC > BM2_MICRO_Q3 > Flashcards

BM2_MICRO_Q3 Flashcards

1
Q

Effect of B19 parvovirus on fetus: *
Hydrops fetalis
Pure red cell aplasia
Fifth Disease
Erythema Infectiosum

A

Hydrops fetalis

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2
Q

What type of specimen would be most appropriate for detection of adenovirus types 40 and 41 infection? *
Blood
Urine
Stool
Swab

A

Stool

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3
Q

Types of Adenoviruses that are found most often in bone marrow and renal transplant recipients. *
Types 15 and 16
Types 11 and 12
Types 40 and 41
Types 34 and 35

A

Types 34 and 35

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4
Q

A 5 yo male child had onset of cough, nasal congestion, fever, and sore throat for 2 days, you suspect that the etiologic agent is an Adenovirus, which specific group of Adenoviruses does the etiologic agent belong? *
Group E
Group C
Group B
Group A

A

Group C

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5
Q

Major sites of Parvovirus replication include: *
fetal bone marrow
ALL blood cells
fetal liver
CNS

A

fetal liver

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6
Q

Which among these blood type is at risk for acquiring Parvovirus B19 infection: *
Duffy
Lewis
P
ABO

A

P

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7
Q

Principal targets for human B19 parvovirus? *
Immature cells in the erythroid series
Mature RBC
Platelets
Immature Leukocytes

A

Immature cells in the erythroid series

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8
Q

Mode of Transmission of Parvovirus: *
Vertical
Parenteral
Respiratory
All are correct

A

Respiratory

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9
Q

a 30 yo G2P1 (1001) 19 weeks Age of Gestation, mother came into your clinic, showing signs and symptoms of Parvovirus B19 Infection, what is the probable outcome of her pregnancy: *
Fetal demise
All are correct
Healthy baby
Baby will produce antibody against B19

A

Fetal demise

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10
Q

Treatment of Adenoviruses infection: *
None
Remdesivir
Azithromycin
Cefuroxime

A

None

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11
Q

Property/ies of Adenoviruses: *

Replication in the cytosol
RNA, linear, 26–45 kbp, protein bound to termini, infectious
With envelope
Adenoviruses replicate well only in cells of epithelial origin.

A

Adenoviruses replicate well only in cells of epithelial origin.

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12
Q

The following are commonly used urinary antiseptics:
Chloramphenicol
Ampicillin
Nalidixic acid
Metronidazole

A

Nalidixic acid

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13
Q

TRUE of Erythema Infectiosum (Fifth Disease): *

The incubation period is usually 4-5 weeks but may extend to 6 weeks.
Specific IgM antibodies appear about 15 days postinfection.
This erythematous illness is most common in children of early school age and occasionally affects adults. Fever and mild constitutional symptoms may accompany the rash, which has a typical “slapped cheek” appearance
All are correct

A

This erythematous illness is most common in children of early school age and occasionally affects adults. Fever and mild constitutional symptoms may accompany the rash, which has a typical “slapped cheek” appearance

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14
Q

These serotypes of Adenoviruses are etiologically associated with infantile gastroenteritis *
Serotypes 15 and 41
Serotypes 40 and 41
Serotypes 10 and 11
Serotypes 30 and 32

A

Serotypes 40 and 41

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15
Q

Cytomegalovirus affects the organs in latent infection except *

Kidneys
Glands
Lymphoid tissue
Neurons

A

Neurons

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16
Q

The common name of Human Herpes 8 is *

Epstein-Barr
Herpes Simplex
Kaposi sarcoma
Varicella-zoster

A

Kaposi sarcoma

17
Q

The assembly of the virus particle from the manufactured components is a complex process. Some of the particles are released from the cell by budding, but the majority of poxvirus particles *

transfer to another cell for further replication
mutate to a more virulent virus
remain within the host cell
die

A

remain within the host cell

18
Q

Primary host of ORF Virus: *
Cow
humans
rodents
Sheep

A

Sheep

19
Q

Replication site of Poxvirus: *
Mitochondria
Golgi apparatus
Cytoplasm
Nucleus

A

Cytoplasm

20
Q

The portal of entry of variola virus: *
break in the skin
ingestion
mucous membranes of the upper respiratory tract
All are correct

A

mucous membranes of the upper respiratory tract

21
Q

when the variola virus enters the body, all of the following will take place EXCEPT: *
NO EXCEPTION
transient viremia and infection of reticuloendothelial cells throughout the body xxx
primary multiplication in the lymphoid tissue draining the site of entry xxx
a secondary phase of multiplication in those cells, leading to a secondary, more intense viremia; and the clinical disease

A

NO EXCEPTION

22
Q

The incubation period of variola (smallpox) *
1 month
1-2 days
10-14 days
1-5 days

A

10-14 days

23
Q

The etiologic agent of contagious pustular dermatitis or sore mouth infection. *
Tanapox
Molluscum contagiosum
Variola
Orf virus infection

A

Orf virus infection

24
Q

which of the following elements prevents inactivation of Poliovirus? *
Iron
sodium deoxycholate
Magnesium
ether

A

Magnesium

25
Q

Primary multiplication site of Poliovirus? *
Intestine
Brain
Mouth
blood

A

Intestine

26
Q

Most common manifestation/form of Poliovirus infection? *

The predominating complaint is flaccid paralysis resulting from lower motor neuron damage.
A recrudescence of paralysis and muscle wasting has been observed in individuals decades after their experience with paralytic poliomyelitis.
stiffness and pain in the back and neck. The disease lasts 2–10 days, and recovery is rapid and complete.
complete.
The patient has only a minor illness, characterized by fever, malaise, drowsiness, headache, nausea, vomiting, constipation, and sore throat in various combinations. Recovery occurs in a few days

A

The patient has only a minor illness, characterized by fever, malaise, drowsiness, headache, nausea, vomiting, constipation, and sore throat in various combinations. Recovery occurs in a few days

27
Q

They are the most commonly recovered agents from people with mild upper respiratory illnesses. They are usually isolated from nasopharyngeal secretions but may also be found in throat and oral secretions. *

Rotaviruses
Rhinoviruses
Poxvirus
Vaccinia virus

A

Rhinoviruses

28
Q

Rhinoviruses grow better at what temperature? *
18C
22C
28C
33C

A

33C

29
Q

The natural reservoir of cowpox: *
human
fox
rodent
cattle

A

rodent

30
Q

How to diagnose Molluscum contagiosum? *
Electron Microscopy
Clinical
PCR
Culture

A

Clinical

31
Q

Natural host of Tanapox virus? *
Sheep
Monkey
Cow
Human

A

Monkey

32
Q

The picornavirus replication cycle occurs in the: *
Endoplasmic Reticulum
Nucleus
Cytoplasm of cells
Golgi apparatus

A

Cytoplasm of cells

33
Q

TRUE of poliovirus: *

Most strains will infect monkeys when inoculated directly into the brain or spinal cord
Poliovirus does not require a primate-specific membrane receptor for infection, and the absence of this receptor on the surface of nonprimate cells makes them virus resistant.
ALL are TRUE
There are three antigenic types of polioviruses based on epitopes found in the P1, P2, and P3 proteins

A

Most strains will infect monkeys when inoculated directly into the brain or spinal cord

34
Q

A 20 yo female present with abrupt onset of fever and stabbing chest pain which is preceded by malaise, headache, and anorexia. Based on the history, the chest pain was noted for more than a week now. There is also associated abdominal pain. What do you think is the etiologic agent? *
group D coxsackieviruses
group C coxsackieviruses
group A coxsackieviruses
group B coxsackieviruses

A

group B coxsackieviruses

35
Q

The incubation period of coxsackievirus infection ranges from: *
14 days
2-9 days
1-2 days
1 month

A

2-9 days

36
Q

emerged as a cause of severe hand-foot-and-mouth disease, sometimes followed by nail shedding *
group B coxsackieviruses
Coxsackievirus A6
coxsackievirus A16
group C viruses

A

Coxsackievirus A6

37
Q

chief cause of acute hemorrhagic conjunctivitis: *
group B coxsackieviruses
Coxsackievirus A6
Enterovirus 70
coxsackievirus A16

A

Enterovirus 70

38
Q

sequelae of acute hemorrhagic conjunctivitis: *
sepsis
None
Blindness
cataract formation

A

None

BM2 RC (7 decks)

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