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BM2 MICRO QUIZ 2 Flashcards

1
Q

Shepherd’s crook are morphologic features of *
M. leprae
M. marinum
M. avium complex
M. kansasii

A

M. kansasii

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2
Q

Which of the following is not true about positive tuberculin test result ? *

Persons are at risk of developing disease from reactivation of the primary infection,
An individual has been infected in the past
Negative persons have never been infected
It does not imply that active disease or immunity to disease is present

A

Negative persons have never been infected

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3
Q

All of the following are true about FTA-ABS, EXCEPT: *

A negative FTA-ABS result on CSF tends to exclude neurosyphilis
Positive FTA- ABS result on CSF can occur by transfer of antibodies from serum and is not helpful in the diagnosis of neurosyphilis
The presence of IgG FTA in the blood of newborns is a good evidence of in utero infection
The test uses indirect immunofluorescence to detect reactive antibodies

A

The presence of IgG FTA in the blood of newborns is a good evidence of in utero infection

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4
Q

One is NOT a first-line drugs in treating tuberculosis *

Isoniazid
Amikacin
Rifampicin
Pyrazinamide

A

Amikacin

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5
Q

All of the following can kill Treponema pallidum, EXCEPT: *

Penicillin
Heat (32C)
Bismuth
Drying

A

Heat 32C

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6
Q

It has been cultured from hot and cold water taps, hospital hot water generators and storage tanks, and other environmental sources *

M. genavense
M. xenopi
M. kansasii
M. marinum

A

M. xenopi

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7
Q

Growth on solid media in < 7days *

Scotochromogen
Non chromogen
Rapid grower
Photochromogen

A

rapid grower

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8
Q

Mycoplasma pneumoniae is transmitted from person to person by means of *

Respiratory secretions
Aerosol
all are possible
fecal-oral route

A

respiratory secretions

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9
Q

One of these does NOT demonstrates YELLOW-ORANGE fluorescence after staining *

Acid-Fast
All of the above
Auramine
Rhodamine

A

acid fast

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10
Q

Agglutinating leptospiral antibodies first appear 5–7 days after infection and develop slowly, reaching a peak at *

9-10 weeks
1-2 weeks
3-4 weeks
5-8 weeks

A

5-8 weeks

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11
Q

Leptospirae can survive for weeks in water given which condition? *

Alkaline water
Rat infested water
Acidic water
Dirty water

A

alkaline water

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12
Q

Mycobacterium avium complex are treated with *

D. B and C
A. INH, RIF, PZA
B. Clarithromycin or Arithromycin
C. Rifabutin, Clofazisime, Fluoroquinoles

A

B and C

B. Clarithromycin or Arithromycin
C. Rifabutin, Clofazisime, Fluoroquinoles

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13
Q

This type of TB specie is very common in AIDS patients and occurs in other
immunosuppressed patients *

M. tuberculosis
M. bovis
M. avium complex
M. leprae

A

M. avium complex

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14
Q

The risk of developing disseminated MAC infection in HIV-infected persons is greatly increased *

CD4-positive lymphocyte count declines to below 100/μL
CD4-positive lymphocyte count declines to above 100/μL
If the patient is a homosexual
All of the above

A

CD4-positive lymphocyte count declines to BELOW 100/μL

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15
Q

IIn women, M genitalium has been associated with a variety of conditions which include: *

Oophoritis
Cervical polyp
Infertility
Endometriosis

A

INFERTILITY

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16
Q

This is known as yellow bacillus *

M. kansasii
M. marinum
M. genavense
M. xenopi

A

M. kansasii

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17
Q

Lady Windermere syndrome is described to a patient having the following criteria*

pulmonary MAC
absence of chronic lung disease
all of the above
middle aged to elderly women

A

all of the above

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18
Q

This is referred as tap water bacillus *

M. leprae
M. avium
M. szulgai
M. gordonae

A

M. gordonae

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19
Q

This is known as swimming pool granuloma or fish tank granuloma *

M. kansasii
M. xenopi
M. marinum
M. fortuitum

A

M. marinum

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20
Q

Which of the following are eponyms for disease caused by M. ulcerans? *

Bairnsdale ulcer
Buruli ulcer
Buruli disease
All of the above

A

all of the above

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21
Q

This method is based on development of profiles of mycolic acids *

High performance liquid chromatography (HPLC)
All of the above
Matrix assisted laser desorption ionization- time of flight mass spectrometry (MALDI-TOF MS)
Molecular probe methods

A

High performance liquid chromatography (HPLC)

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22
Q

One is not true about Interferon Gamma Release Assays (IGRA) *

These assays are based on the host’s immune responses to specific M. tuberculosis antigens
ESAT-6 (early secretory antigenic target-6) and CFP-10 (culture filtrate protein-10)
Utilizes an enzyme linked immunoassay in whole blood or purified peripheral blood
mononuclear cells
Can be used in children less than 2 years old
None of the above

A

Can be used in children less than 2 years old

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23
Q

Hansen’s disease *

M. tuberculosis
M. chelonae
M. fortuitum
M. leprae

A

M. leprae

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24
Q

One of the rapid growers mycobacteria which is multidrug resistant includes *

M. chelonae
M. abscessus
All of the above
M. fortuitum complex

A

M. abcessus

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25
Q

Rickettsia akari has its vector in bloodsucking mites of the species *

Glaucomys volans
Allodermanyssus sanguineus
Dermacentor andersoni
Pediculus corporis

A

Allodermanyssus sanguineus

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26
Q

the most important indication for intravenous clindamycin is the treatment of patients with: *
Pneumonia
meningitis
severe anaerobic infections
colitis

A

severe anaerobic infections

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27
Q

Rickettsial growth is enhanced in the presence of what antibiotics? *

All of the above
Chloramphenicol
Tetracyclines
Sulfonamides

A

sulfonamides

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28
Q

Southern flying squirrel is an extrahuman reservoir of what Rickettsia specie?*

Orientia tsutsugamushi
Rickettsia typhi
Rickettsia rickettsii
Rickettsia Prowazekii

A

Rickettsia prowazekii

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29
Q

Eschar is prominent in the following infection caused by *

Rickettsia sibirica
Rickettsia conorii
Rickettsia akari
All of the above

A

all of the above

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30
Q

Sheeps, cattle and goats are the mammalian reservoir of which of the
following? *

Rickettsia akari
Anaplasma phagocyticum
Erlichia chaffeensis
Coxiella burnetii

A

coxiella burnetii

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31
Q

The drug of choice in the treatment of acute Q fever? *

Doxycycline
Chloramphenicol
Sulfonamides
Metronidazole

A

doxycycline

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32
Q

Humans are the mammalian reservoir of *

Rickettsia rickettsii
Rickettsia typhi
Orientia tsustsugamushi
Rickettssia prowazekii

A

Rickettsia prowazekii

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33
Q

Rocky Mountain Spotted Fever do not have this clinical feature *

Rash
Fever
Eschar
Myalgia

34
Q

Pasteurization at 71.5 degree celsius for 15 seconds are adequate to destroy viable related genera of Rickettsia *

Rickettsia akari
Coxiella burnettii
Ehrlichia chaffeensis
Anaplasma phagocytophilum

A

COxiella burnettii

35
Q

Drug of choice for Rickettsiae: *

Doxycyxline
Amikacin
Ceftriaxone
Penicillin G

A

doxycycline

36
Q

Drugs that are primarily used to treat Mycobacterial Infections *

Isoniazid
All are correct
Rifampicin
Ethambutol

A

all are correct

37
Q

This stains only with Gimenez *

Ehrlichia chaffeensis
All of the above
Coxiella burnetti
Ehrlichia ewingii

A

coxiella burnetti

38
Q

This causes a flea-borne typhus *

Orientia tsutsugamushif
Rickettsia typhi
Rickettsia prowazekii
Rickettsia rickettsii

A

rickettsia typhi

39
Q

Which of the following drugs is a fourth-generation cephalosporins: *

Cefoxitin
Ceftazidime
Cefepime
Cefazolin

40
Q

Drug of choice for Leptospira: *

TMP-SMZ
Ceftriaxone
Amikacin
Penicillin G

A

Penicillin G

41
Q

These are important in the humoral immune response and provide the basis for serotyping in Rickettsia. *

Diaminopimelic acid
Muramic acid
Omp A and B
Lipopolysaccharides

A

Omp A and B

42
Q

Isolation of Rickettsiae should be done only in what type of laboratory? *

Reference
Secondary
Tertiary
Primary

43
Q

Which of the following are reservoir of Erlichia ewingii? *

Mice
Marsupials
Dogs
Rodents

44
Q

This Rickettsia specie causes mild disease with a rash resembling that of
varicella *

Rickettsia prowazekii
Orientia tsutsugamushi
Rickettsia akari
Rickettsia typhi

A

Rickettsia akari

45
Q

Orientia tsutsugamushi belongs to what Rickettsial infection group? *

Epidemic typhus
Endemic typhus
Scrub typhus
Traditional group

A

scrub typhus

46
Q

Dermacentor andersoni is the vector of what Rickettsia specie? *

Rickettsia typhi
Rickettsia rickettsii
Rickettsia prowazekii
Rickettsia akari

A

rickettsia rickettsii

47
Q

Brill -Zinsser disease is associated with what Rickettsia infection disease? *

Epidemic typhus
Spotted fever group
Endemic murine typhus
Scrub typhus

A

epidemic typhus

48
Q

Anticoagulant of choice for blood sample in the detection of erlichiae using
Polymerase Chain Reaction *

Ethylenediamenetetracetic acid
Heparin
Sodium oxalate
Sodium fluoride

A

Ethylenediamenetetracetic acid

ethyl-ene-diamene-tetracetic

49
Q

Presence of inclusions in the circulating white blood cells are diagnostic tests of *

All of the above
Erlichia ewingii
Anaplasma phagocytophilum
Erlichia chaffeensis

A

all of the above

50
Q

Rat fleas carry the rickettsiae from rat to rat and from rat to humans *

Rickettsia akari
Rickettsia prowazekii
Orientia tsustsugamushi
Rickettsia typhi

A

rickettssia typhi

51
Q

Pediculus humanus corporis and Pediculus humanus capitis are vectors of *

Rickettsia prowazekii
Rickettsia rickettsii
Rickettsia akari
Rickettsia typhi

A

rickettsia prowazekii

52
Q

True reservoir of Orientia tsutsugamushi *

Marsupials
Mites
Dogs
Mice

53
Q

Treatment of Leprosy: *

Dapsone + Rifampin
Ethambutol + Rifampin
Rifampin + Ethambutol
Dapsone + Ethambutol

A

Dapsone + Rifampin

54
Q

This causes human monocyte ehrlichiosis (HME) *

Erlichia ewingii
Erlichia chaffeensis
All of the above
Anaplasma phagocytophilum

A

Erlichia chaffeensis

55
Q

Which of the following stains are the most useful methods for confirming Rickettsial infections? *

Gimenez and Acridine
Giemsa and Gram
Immunofluorescence and Immunostains
All of the above

A

Immunofluorescence and Immunostains

56
Q

Human urine may contain Leptospira during this time: *

1-2 days
3-4 days
1-2 weeks
2-3 weeks

57
Q

What is your report if the smear of sputum shows 1-9 AFB per field using Carbol fuschsin stain? *All of the following can kill Treponema pallidum

3+
4+
1+
2+

58
Q

Which among these tests is used to diagnose neurosyphilis? *

FTA-ABS
VDRL
RPR
toluidine red unheated serum test

59
Q

Leprospire grow best under what condition? *

Aerobic
Microaerophilic
Anaerobic
Presence of CO2

60
Q

Organism(s) associated with Lyme Disease *

ALL are CORRECT
Borrelia afzelii
Borrelia burgdorferi sensu stricto
Borrelia garinii

A

ALL are CORRECT

61
Q

On culture, which of the following organisms will have a “fried egg” appearance? *

Mycoplasma hominis
Mycoplasma pneumoniae
Mycoplasma genitalium
Ureaplasma urealyticum

A

Mycoplasma hominis

62
Q

Lesions demonstrate noncaseating granulomas in the nerves and dermis, extending to involve the basal layer of the epidermis; few, if any, AFB are present *

All of the above
Lepromatous leprosy
Borderline leprosy
Tuberculoid leprosy

A

Lepromatous leprosy

63
Q

This is the effective antibiotic for the refractory cases of Lyme disease: *

Penicillin G
Amoxicillin
Ceftriaxone
Doxycycline

A

Ceftriaxone

64
Q

This has the widespread anergic form of the disease *

C. Borderline leprosy
B. Tuberculoid leprosy
D. B and C
A. Lepromatous leprosy

A

A. Lepromatous leprosy

65
Q

A 20 year old male came in to your clinic with a chief complaint of dysuria, denied having recent sexual intercourse. Which of the following organisms are considered to be a possible etiologic agent? *

Escherichia coli
Staphylococcus aureus
Ureaplasma urealyticum
Mycoplasma hominis

A

Ureaplasma urealyticum

66
Q

The most common pathologic findings in complicated cases of Mycoplasma pneumoniae infection is: *

necrotizing enterocolitis
sepsis
All are correct
interstitial with peribronchial pneumonitis

A

interstitial with peribronchial pneumonitis

67
Q

When does a pregnant woman with syphilis can transmit Tryponema pallidum to the fetus through the placenta? *

20-24 weeks AOG
4-8 weeks AOG
10-15 weeks AOG
35-39 weeks AOG

A

10-15 weeks AOG

68
Q

Incubation period of Leptospirosis: *

3-4 weeks
1-2 weeks
1-2 days
3-4 days

69
Q

LöwensteinJensen is a what type of media *

None of the above
Broth
Inspissated egg
Semisynthetic

A

Inspissated egg

70
Q

The spirochete B burgdorferi is transmitted to humans by the bite of: *

Ixodes tick
Anopheles mosquito
Reduviid bug
O tsutsugamushi

A

Ixodes tick

71
Q

n leptospirosis, the principal sources of human infection include the following, EXCEPT: *

Wild Rodents
Cattle
Goat
Pig

72
Q

n leptospirosis, the principal sources of human infection include the following, EXCEPT: *

Wild Rodents
Cattle
Goat
Pig

73
Q

characteristic skin lesion of Lyme disease: *

Necrotizing fasciitis
Impetigo
Erythema migrans
Silver scaling

A

Erythema migrans

74
Q

TRUE of Mycoplasma hominis: *

Women with salpingitis more commonly have antibodies against M hominis than women with no disease.
M hominis can be cultured from the upper urinary tract in about 10% of patients with pyelonephritis.
M hominis is strongly associated with infection of the uterine tubes (salpingitis) and tubo-ovarian abscesses; the organism can be isolated from the uterine tubes of about 10% of patients with salpingitis but not from women with no signs of disease.
ALL are Correct

A

ALL are Correct

75
Q

The events in Mycoplasma infection are less well understood but may include several factors and it include all of the following EXCEPT: *

competition for and depletion of nutrients.
cell-mediated immunity
cytolysis mediated by antigen–antibody reactions or by chemotaxis and action of mononuclear cells
direct cytotoxicity

A

cell-mediated immunity

76
Q

These following therapeutic drug(s) can be given to patient who has Mycoplasma infection, except? *

Erythromycin
Tetracycline
Azithromycin
Penicillin

A

Penicillin

77
Q

These develop pigment when growing in the dark *

Nonchromogens
All of the above
Photochromogens
Scotochromogens

A

Scotochromogens

78
Q

Which of the following statement is FALSE? *

If the RPR result is negative, then additional testing with a traditional treponemal test such as the TP-PA is recommended.
If the RPR result is positive, a current or past infection with syphilis is likely.
If the TP-PA result is positive, syphilis is likely
ALL are correct

A

ALL are correct

79
Q

Which of the following organs are mainly affected by Leptospirosis? *

Spleen
Adrenal glands
Pancreas
Kidney

80
Q

Which among these tests is used to diagnose neurosyphilis? *

VDRL
unheated serum reagin
RPR
toluidine red unheated serum test

81
Q

N-acetyl-L-cysteine decontaminated with NaOH kills many other bacteria and fungi in the specimens like *

Gastric washings
Sputum
Blood
CSF

BM2 RC (7 decks)

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