Blood Pressure Regulation and pH Balance Flashcards
Stimulus
Fluid loss decreases blood pressure
Sensor
Drop in blood pressure detected by receptors in the juxtaglomerular apparatus (found neat glomerulus)
Control Center, Effector, and Action
Detection causes juxtaglomerular apparatus to release renin which takes angiotensinogen (enzyme precursor made by liver) and turns it into active angiotensin
Action 1
Angiotensin constricts blood vessels which increases blood pressure
Effector and Action 2
Angiotensin stimulates release of aldosterone from adrenal cortex which causes distal tubule to reabsorb Na+, causing Cl- to follow - increases osmotic gradient, causing water to move out of nephron, increasing fluid level in blood and bp
pH Balance
Buffer system absorbs excess H+ ions and bases in blood
Buffer System
H+ buffered by bicarbonate ions in blood: H+ + HCO3- –> H2CO3
- H2CO3 breaks down to water and CO2
- Kidneys can restore buffer when needed by recombining CO2 and water to make H+ and HCO3- (H+ can go on to combine with other things and be excreted in urine)