Blood pressure L12 & L13 Flashcards
What percentage of the blood distribution in the cardiovascular system is located in the systemic veins and venules?
64%
-they are the blood reservoirs of the body
What does 64% resemble in relation to the blood distribution in the cardiovascular system?
systemic veins and venules’ reservoirs of blood
What percentage of the blood distribution in the cardiovascular system is located in the systemic arteries and arterioles?
13%
What does 13% resemble in relation to the blood distribution in the cardiovascular system?
Systemic arteries and arterioles
What percentage of the blood distribution in the cardiovascular system is located in the Pulmonary Vessels?
9% in the Right circuit ALTOGETHER
What does the 9% resemble in relation to the blood distribution in the cardiovascular system?
pulmonary circuit ALTOGETHER (of the right side)
What percentage of the blood distribution in the cardiovascular system is located in the heart?
7%
What does the 7% resemble in relation to the blood distribution in the cardiovascular system?
percentage in the heart
or
percentage in the systemic capillaries
What percentage of the blood distribution in the cardiovascular system is located in the systemic capillaries?
7%
site of exchange has Smallest amount of blood in the systemic circuit
What does the 7% resemble i relation to the blood distribution in the cardiovascular system?
percentage in the systemic capillaries
or
percentage in the heart
Where is there an overlap in identical percentages of the distribution of blood in the cardiovascular system?
Heart and the Systemic Capillaries (side of exchange has smallest amount of blood in the systemic circuit)
both contain 7% of blood
Where is the blood distribution in the cardiovascular system both 7%?
Heart
and the Systemic Capillaries (side of exchange has smallest amount of blood in the systemic circuit)
What percentage of the blood distribution in the cardiovascular system is located in the systemic circuit?
84%
64% + 13% + 7% = 84%
Veins are the reservoirs, so always more than arteries
Systemic veins and venules: 64%
Systemic arteries and arterioles: 13%
Systemic capillaries: 7% (same proportion as in heart- emphasises is so small, as is the smallest in systemic circuit as is the site of exchange (small and slow blood flow (1 RBC diameter of endothelium)))
What is the breakdown of percentages of the blood distributed in the cardiovascular system?
- Systemic Veins and Venules: 64%
- Systemis arteries and Arterioles: 13%
- Pulmonary circuit: 9%
- Heart: 7% (same as S.c)
- Systemic Capillaries: 7% (same as H. and is small((est) proportionately) as is slow site of exchange)
What contains the largest percentage of blood?
Systemic veins and venules (reservoirs) 64% out of total 84%
allows diversion of blood if the need quickly arises
done through vasoconstriction and vasodilation
Why do we have blood reservoirs?
allows diversion of blood if the need quickly arises
done through vasoconstriction and vasodilation
How do we divert blood reservoirs?
located in systemic veins (and venules)
done through RESERVOIR IN VEINS (vaso-) constricting (constriction) = vasoconstriction
done through RESERVOIR IN VEINS (vaso-) dilating (dilation) = vasodilation
What is the relationship between vasoconstriction/dilation and blood reservoirs?
vaso = veins
veins = are the blood reservoirs
therefore in order to divert blood reservoirs if quick demand arises you vasoconstrict and vasodilate
What does 120/80 mean?
Diastolic (press) /systolic (press)
What does the 80 in 120/80 mean?
Systolic pressure
What does 120 in 120/80 mean?
Diastolic pressure
Where is diastolic pressure mentioned?
in 120 in 120/80
Where is systolic pressure mentioned?
in 80 in 120/80
What are the diastolic/systolic pressures for when you have hypertension?
> 140/>90
What are the diastolic/systolic pressures for when you have a short life expectancy due to poor heart conditions?
200/140
What is hypertension a precursor to?
A whole bunch of cardiovascular problems
What are some risk factors of hypertension?
smoking
excess alcohol/binge drinking
obesity
lack of exercise
When the heart enlargens does the ejection fraction increase or decrease?
decrease
- as larger EDV
- can also result in short breath, venous congestion and heart failure (dilated cardio myopathy)
What can cause arteries to be weak?
Tortuosity = sharp bends
Plaques = blockage
weak points = rupture easily under high pressure
Can results in stroke or a coronary tear
What are the body’s major resistance vessel?
arteioles
Where is there a biggest amplitude in diastolic and systolic pressure
in the arteries and arterioles
Where is there the biggest reduction in amplitudes of diastolic and systolic pressure, and huge reduction of BP as well?
In arterioles
- SM allows this absorption of pressure and greatest resistance, to decrease amplitude
- enough to dampen pressure to give resistance to flow
When is there a pulsatile pressure big enough to be measured by a sphygmomanometer?
in the arteries and arterioles
What is the equation for MABP?
CO x TPR
What does CO cardiac output x TPR =?
MABP mean arterial blood pressure
TPR times what equals MABP?
Cardiac Output
CO x TPR = MABP
What is the equation of EF?
SV / EDV = (EDV-ESV) DIVIDED by EDV
e.g. on pressure-volume loop 80mL/120mL
Why is the flow rate in capillaries the same?
As Blood pressure Drives exchange
What is the driving force of filtration (NFP)?
Blood pressure
BP drives NFP
so in capillaries bp varies, BF stays relatively constant (Flowin=Flowout) - Flow rate is the same as BP drives exchange
That is why blood pressure has to be kept constant, as it drives exchange, which allows the muscle to have a constant supply of oxygen and nutrients
without constant blood pressure, the metabolising muscle wont get enough oxygen for energy or nutrients for nourishment, and there will be excess metabolic waste products and CO2 in the system
Where does 2x way exchange in the body occur?
In the capillaries
Capillary IF Cells
Is the Blood Hydrostatic pressure largest on the arterial initial or venous end of the capillary?
Arterial end,
due to the pressure drop at the arteriole end, which drives filtration
What type of condition is hypertension?
Chronic, high blood pressure
What do you have when you have chronic high blood pressure?
Hypertension
What happens if you have longterm hypertension?
Increased MABP Longterm
What is the relationship between longterm MABP/hypertension and Edema?
Long term MABP = increased Net Filtration = increased fluid out of capillaries =increased fluid into tissue (esp in lower limbs) =decreased reabsorption =edema = swollen tissue in lower limbs =swollen ankles (feet or legs)
What is the NFP?
Net filtration pressure
What is the equation for Net filtration pressure?
=(BHP+IFOP) - (BCOP+IFHP)
=Pressures driving filtration - pressures driving reabsorption
What is the equation (BHP+IFOP) - (BCOP+IFHP) for?
NFP
Net Filtration Pressure
Essentially what does (BHP+IFOP) - (BCOP+IFHP) mean?
Pressures driving filtration - pressures driving reabsorption
Is the Blood Hydrostatic pressure smallest on the arterial initial or venous end of the capillary?
venous end of the capillary
as it has been filtered and re-absorbed and lost pressure
as the blood had to travel down a pressure gradient
What are the pressures the are going out of the capillary?
BHP
IFOP
What are the pressures driving filtration?
BHP
IFOP
What are the pressures that are going into the capillary?
BCOP
IFHP
What are the pressures driving absorption?
BCOP
IFHP
What are the changes between the Net filtration and Net reabsorption as you go from arterial to venous end of the capillaries?
BHP is the only element of the ((BHP+IFOP) - (BCOP+IFHP)) equation to change
What is the pressure of BHP at the arterial end of the capillary?
35mmHg
What is the pressure of 35mmHg referring to in the capillaries?
BHP on the arterial end
What is the pressure of IFOP in the capillary?
1 mmHg
What is the pressure of 1 mmHg referring to in the capillaries?
IFOP
What is the pressure of BCOP at the arterial end of the capillary?
26mmHg
What is the pressure of 26mmHg referring to in the capillaries?
BCOP -at BOTH the arterial and venous end of the capillary - only BHP changes