Blood Films Flashcards
TARGET CELLS
SEEN IN: Sickle-cell/thalassaemia Iron-deficiency anaemia Hyposplenism Liver disease
‘TEAR-DROP’ POIKILOCYTES
SEEN IN Myelofibrosis
SPHEROCYTES
SEEN IN:
Hereditary spherocytosis
Autoimmune hemolytic anaemia
BASOPHILIC STIPPLING
SEEN IN: Lead poisoning Thalassaemia Sideroblastic anemia Myelodysplasia
HOWELL-JOLLY BODIES
SEEN IN Hyposplenism (seen in Coeliac)
HEINZ BODIES
SEEN IN:
G6PD deficiency
Alpha-thalassaemia
SCHISTOCYTES (‘Helmet cells’)
SEEN IN:
Intravascular haemolysis
Mechanical heart valve
Disseminated intravascular coagulation
‘PENCIL’ POIKILOCYTES
SEEN IN Iron Deficiency Anaemia
BURR CELLS (ECHINOCYTES)
SEEN IN:
Uraemia
Pyruvate kinase deficiency
ACANTHOCYTES
SEEN IN Abetalipoproteinemia, Hyposplenism
HYPERSEGMENTED NEUTROPHILS
SEEN IN Megaloblastic Anaemia - VIT B12 Deficiency
Hyposplenism eg post-splenectomy
Target cells Howell-Jolly bodies Pappenheimer bodies Siderotic granules Acanthocytes
IDA
Target cells
‘Pencil poikilocytes’
If combined with B12/Folate deficiency = DIMORPHIC FILM - mixed microcytic + macrocytic
Myelofibrosis
Tear Drop poikilocytes
Intravascular Haemolysis
Schistocytes
Megaloblastic Anaemia
Hypersegmented neutrophils
Coeliac Disease
Howell-Jolly bodies (Hyposplenism)
Pencil poikilocytes (IDA)
Both features of Coeliac disease!
ATYPICAL LYMPHOCYTES
Glandular Fever
Infectious Mononucleosis
Blood Film of AML
Myeloid blasts
Auer rods
Myelodysplasia Blood Film
Myelodysplasia typically results in red cells of abnormal shapes (poikilocytosis) and sizes (anisocytosis) with Pappenheimer bodies (abnormal granules of iron).
