Acute Lymphoblastic Leukaemia

Question 1

Acute Lymphoblastic Leukaemia - Good prognostic factors

Answer 1

GOOD PROGNOSIS

• FAB L1 type
• Common ALL
• Pre-B phenotype
• Low initial WBC
• Del (9p)

Question 2

Acute Lymphoblastic Leukaemias - Bad prognostic factors

Answer 2

BAD PROGNOSIS

• FAB L3 type
• T or B cell surface markers
• Philadelphia translocation (9:22)
• Age <2 or >10
• Male
• CNS involvement
• High initial WBC (>100 X 10^9)
• Non Caucasian