Blood Bank Flashcards

1
Q

Hgb /Hct requirement for donation

A

> = 12.5 or >= 38%

For autologous ; >= 11 or >= 33%

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2
Q

Giver the deferral time

Etretinate (Tegison) : 
Acitretin (Soriatane): 
Isoretinoin: 
Dutasteride (Avodart): 
Finasteride: 
Aspirin : 
Warfarin : 
Plavix (Clopidogrel) : 
Ticlid (Ticlopidine) : 
HBIG:
A
Etretinate (Tegison) :  Indefinate
Acitretin (Soriatane):  3 years
Isoretinoin: 1 month
Dutasteride (Avodart): 6 months 
Finasteride: 1 month
Aspirin : 48 hours
Warfarin : 1 week 
Plavix (Clopidogrel) : 14 days 
Ticlid (Ticlopidine) : 14 days
HBIG: 1 year
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3
Q

Volume collected =

A

10.5m./kg

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4
Q

Give the deferral time

Measles, Mumps, Polio, Yellow fever, Typhoid

Rubella , Varicella

A

Measles, Mumps, Polio, Yellow fever, Typhoid = 2 weeks

Rubella , Varicella = 4 weeks

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5
Q

Calculate the dosage of RhIg

A

Maternal BV x % of the kleihauer-Betke / 30

Round up/down and add 1

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6
Q

Expiration:

CPD, ACD, CP2D
CPDA
CPD-AS

A

CPD : 21
CPDA : 35
CDP-AS :42

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7
Q
For RBCs
Stored at what temperature:
Hct: 
Hgb: 
If leukoreduced:
A

Stored at what temperature: 1-6 C
Hct: <80%
Hgb: 50g in 95%
If leukoreduced: <= 5 x 10 ^6 in 95%, retain 85% of RBC

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8
Q

RBC:

Total volume 
RBCs
Plasma
Iron
WBC
Anticoagulant
A
Total volume : 350 ml
RBCs : 200-250
Plasma : <50ml
Iron : 200-250 mg
WBC : 10^9, unless leukoreduced
Anticoagulant: 63 or 70 ml
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9
Q

Frozen RBC are kept at ___ C for ___ years

A

Frozen RBC are kept at -65 C for 10 years

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10
Q

Platelets are kept for: ___days at _____ C

A

5 days at 20- 24 C

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11
Q

WBD plts

Volume
Plt count
WBCs
pH

A

Volume: 40-60 (plasma)
Plt count >5.5 x 10^10 in 90%
WBCs 10^7 or <8.3 x 10^5 if leukoreduced
pH>6.2 in 90%

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12
Q

Apheresis plts

Volume
Plt count
WBCs
pH

A

Volume: 100-150
Plt count: > 3 x 10^11 in 90%
WBCs: < 5 x 10^6
pH>6.2 in 90%

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13
Q

FFP:

1 year at
7 years at
24 hours at

A

1 year at -18 C
7 years at - 65 C
24 hours at 1-6 C after thaw

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14
Q

Cryo:

1 year at
6 hours

A

1 year at -18 C

6 hours 20-24 C after thaw, 4 hours if pooled

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15
Q

FFP

Volume
Coag factors
Fibrinogen

A

Volume : 200-250
Coag factors : 1IU/ml of all coag factors
Fibrinogen : 400 mg

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16
Q

Cryo

Volume
Fibrinogen
Factor 8
vWF
Factor 13
Fibronectin
A
Volume 15ml
Fibrinogen: >150 mg
Factor 8: >80
vWF: 80-120 IU
Factor 13: 40-60 IU
Fibronectin present
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17
Q
Granulocyte
Volume
WBCs
RBC
PLT
A

Volume 200-300
WBCs >1 x 10^10
RBC 20-50
PLT 1 X 10^11

18
Q

FP24 is deplete of which factors?

A

5 and 8

19
Q

Antigens the display dosage?

A

RH, Kid, Duffy, MNS

20
Q

Most common cause of delayed HTR

A

Kidd (severe intravascular hemolysis), C, D, E

21
Q

4 most common cause of HDN

A

AB> C>Kell and Rh

22
Q

Antigens that are enhanced by enzymes

A

ABO-related (ABO,Lewis,I,PP1PK)
Rh
Kidd
“Lewis is a Rotten Peeing Kidd)

23
Q

Antigens that are destroyed by enzymes

A

MNSs, Duffy, Luthern, Chido

24
Q

Commonly produce intravascular hemolysis

A

AB, Kidd, P

25
Q

Antgiens unaffected by enzymes

A

Kell

26
Q

Clinically significant HTLA abs

A

Cartwright (Yt), Holley (Hy) and Gregory (Gy)

27
Q

What does the lectin Arachis hypogaea detect?

A

T activation

T antigen activation occurs through bacterial neuraminidase. Adults normally have Anti-T IgM. Significant in neonates.

28
Q

Ulex europaeus

A

H

29
Q

Dolichos biflorus

A

A1

30
Q

Whats the apheresis category?

Myasthenia gravis

A

1

31
Q

Whats the apheresis category?

chronic inflammaotry demyelinating polyneuropathy (CIDP)

A

1

32
Q

Whats the apheresis category?

Pediatric autoimmune neuropsychiatric disorders associated with streptococaal infections (PANDAS) and Sydenham chorea

A

1

33
Q

Whats the apheresis category?

Goodpasture syndrome

A

1

34
Q

Whats the apheresis category?

Renal transplant, antibody mediate rejection

A

1

35
Q

Whats the apheresis category?

Renal transplant, HLA desensitization or ABO incompatible trantsplant

A

2

36
Q

What is the significant titer for anti-D? Anti-kell?

A

D : >16

Kell: >8

37
Q

Average plt lifespan?

A

9.5 days

38
Q

Causes immediate HTR

A

A, Kell, JKa, Fya

39
Q

HLA Class I is found?

A

In all cells (HLA-A, B, C)

40
Q

HLA class II is found?

A

B cells, macrophages, activated T cells (HLADR,DP,DQ)

41
Q

R0/r’ gives rise to?

A

weak D

Big C in trans of D, The Cepelli effect