Blood Flashcards

1
Q

What is blood?

A

A fluid tissue composed of cells in watery liquid called plasma.

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2
Q

What is blood composed of?

A

Plasma, red blood cells, platelets and white blood cells.

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3
Q

What is the primary function of blood?

A
  • To transport oxygen, carbon dioxide, water, nutrients, hormones, wastes and blood cells around the body.
  • Also fights infections by clotting, temperature regulation and tissue pH regulation.
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4
Q

What is plasma?

A
  • A straw-yellow liquid composed of 92% water, with dissolved salts, sugars, lipids and proteins (e.g anitbodies & hormones) making up the rest.
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5
Q

What is the overall percentage of plasma in blood volume?

A

54%

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6
Q

Where are red blood cells made?

A

Red bone marrow of long bones, e.g the femur.

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7
Q

What are red blood cells also known as?

A

Erythrocytes.

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8
Q

What makes red blood cells unique?

A
  • Biconcave shape, giving a greater surface area for oxygen to diffuse in and out.
  • No nucleus, allowing more space to carry oxygen
  • Smaller than the average cells in order to fit through the various blood vessels in the body.
  • Contain haemoglobin
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9
Q

What is the function of red blood cells?

A

Transporting oxygen around the body.

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10
Q

What percentage of the blood volume do red blood cells make up?

A

45%

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11
Q

How long do red blood cells live for and what happens to them afterwards?

A
  • Live for 120 days
  • Get broken down in the liver
  • Haemoglobin broken down into bilirubin and biliverdin, which are then sent to the gall bladder and secreted in to bile.
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12
Q

What is haemoglobin?

A

A red pigment made from protein. It is a globular protein with a haem (iron-containing) group. The haem group is responsible for carrying oxygen.

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13
Q

How many oxygen molecules can one haemoglobin protein carry?

A

Four oxygen molecules.

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14
Q

What is oxyhaemoglobin?

A

Haemoglobin that is carrying oxygen.

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15
Q

What is deoxyhaemoglobin?

A

When haemoglobin isn’t carrying oxygen.

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16
Q

What are the four blood types of the ABO system?

17
Q

What is a haemolytic transfusion reaction?

A

A potentially fatal reaction that can occur when red blood cells of the wrong type are given during a blood transfusion. Antibodies are made against the foreign molecules causing the cells to break open.

18
Q

What is a universal recipient?

A

People who can generally receive blood transfusions from any blood group. This is type AB

19
Q

What is a universal donor?

A

People who can donate blood to any other blood group. This is type O.
NOTE - people who are blood type O can ONLY receive blood from others that are also type O.

20
Q

What is meant by the statement “Inheritance of blood groups is inherently mendelion in nature”?

A

This means that a person who belongs to blood group A, for example, can have one of two possible genotypes - AA or AO (A is dominant to O).

21
Q

If the rhesus factor (Rh) is present on the red blood cells, the person is said to be ______________________?

A

Rhesus positive (Rh+).

22
Q

If the rhesus factor (Rh) is not present on the red blood cells, the person is said to be _______________________?

A

Rhesus negative (Rh-).

23
Q

What percentage of the blood volume do white blood cells and platelets make up?

24
Q

What is the function of both white blood cells and platelets?

A

Both involved in defence mechanisms within the body.

25
What are white blood cells also known as?
Leucocytes.
26
Where are white blood cells produced?
Bone marrow.
27
What are the two types of white blood cells?
1. Monocytes 2. Lymphocytes
28
What are monocytes?
* Monocytes are a large group of white blood cells that mature into more specific types of white blood cells, such as macrophages. * They tend to have a kidney-shaped or notched nucleus.
29
What is phagocytosis?
The process where foreign particles are ingested (by monocytes).
30
What is the role of lymphocytes?
* Involved in more specific defences within the body and specifically recognise individual pathogens, producing antibodies against them. This inactivates and immobilises the pathogen. * Tend to have a large round nucleus that takes up most of the volume of the cell.
31
What are platelets?
Small, irregular shaped cell fragments that do not have a nucleus.
32
What are platelets also known as?
Thrombocytes.
33
What is the lifespan of platelets?
7 days.
34
What role do platelets have?
Platelets are essential in blood clotting. In this way, platelets help to prevent blood loss and entry of pathogens into the body via a wound.
35
What is haemophilia?
A medical condition in which the ability of the blood to clot is severely reduced, causing the sufferer to bleed severely from even a slight injury.
36
What is deep vein thrombosis (DVT)?
When an unwanted clot is formed, especially deep within the veins of the legs.
37
What is a pulmonary embolism?
A potentially life threatening condition, that occurs when a blood clot moves from the vein and travels to the lungs where it then causes a blockage.
38
How can you prevent DVT?
Taking regular breaks to walk around on flights and long car journeys and wearing compression socks.