Blood Flashcards

1
Q

Matrix is liquid allowing blood cells to travel in the bloodstream

A

Blood

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2
Q

Functions of Blood

A
  • Transport of gases, nutrients, waste products
  • Transport of processed molecules
  • Transport of regulatory molecules
  • Regulation of pH and osmosis
  • Maintenance of body temperature
  • Protects against foreign substances
  • Blood clotting prevents fluid and cell loss
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3
Q

Total blood is approximately ___________

A

5 liters

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4
Q

The pH of blood is?

A

7.35 - 7.45

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5
Q

The temperature of blood is

A

38°C

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6
Q

______ is a sticky, opaque fluid with a
metallic taste

A

Blood

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7
Q

Liters of blood for males

A

5-6 L

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8
Q

Liters of blood for females

A

4-5 L

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9
Q

These are the characteristics of _______
- 55% of total blood
- pale, yellow liquid that surrounds cells
- 91% water, 7% proteins, and 2% other

A

Plasma

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10
Q

3 Plasma proteins

A

Albumin
Globulins
Fibrinogen

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11
Q

This helps maintain water balance and 58% of plasma proteins

A

Albumin

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12
Q

4% of plasma proteins and aids in clot formation

A

Fibrinogen

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13
Q

38% of plasma and helps immune system

A

Globulins

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14
Q

Blood cell production

A

Hematopoiesis

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15
Q

All the formed elements of blood are derived
from a single population of cells called stem
cells, or _________________.

A

hemocytoblasts

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16
Q

Activations of clotting factors result in the conversion of fibrinogen to _____

A

fibrin

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17
Q

Plasma without the clotting factors

A

Serum

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18
Q

This determine the type of formed element
derived from the stem cell

A

Growth factors

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19
Q

Red blood cells have no nuclei or organelles and live for 100-120 days. they are also called as?

A

Erythrocytes

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20
Q

What is the function of erythrocytes?

A

Transport O2 to tissues

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21
Q

RED blood cell production

A

Erythropoiesis

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22
Q

Platelets are also called as?

A

Thrombocytes

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23
Q

Main component of erythrocytes which responsible for the cell’s red color

A

Hemoglobin

24
Q

The protein globin, made up of two alpha and two beta chains that each bound to a _______

A

heme group

[Each heme group groups bears an atom of iron, which can bind to one oxygen molecule]

25
Q

Hemoglobin that is bound to O2 (oxygenated) is ___- color

A

bright red

26
Q

Hemoglobin without the bond of O2 is ______ color

A

darker red

27
Q

What is the waste-product of hemoglobin?

A

Bilirubin

28
Q

Globin chains are broken down to ___________ and used to build new proteins

A

amino acids

29
Q

In heme, the iron is released and transported to the red bone marrow that is also used to produce new hemoglobin

A

Heme group breakdown

30
Q

Old red blood cells are removed from blood by
__________________- in spleen and liver

A

macrophages

31
Q

Bilirubin is taken up by liver and released into
small intestine as part of ______

A

bile

32
Q

WBC are completes cell but lacks hemoglobin

A

Leukocytes

33
Q

The functions of WBC

A
  • Fight infections
  • Remove dead cells and debris by phagocytosis
34
Q

Type of leukocytes that contain specific and large cytoplasmic granules and include neutrophils, eosinophils, and basophils

A

Granulocytes

35
Q

The most common type of WBC, they are the body’s bacteria slayers. It remains in blood for 10 -12 hours then move to tissues

A

Neutrophils

35
Q

This is an accumulation of dead
neutrophils, cell debris and fluid at sites of
infections

A

Pus

36
Q

The least common and it releases histamine and heparin that prevent the formation of clots

A

Basophils

36
Q

Having a two-lobed nucleus, and is involves in reducing inflammation and destroy parasites

A

Eosinophils

37
Q

Very small and have no specific granules

A

Agranulocytes

37
Q

Two kinds of agranulocytes

A

Monocytes and Lymphocytes

38
Q

The smallest WBC and plays a role in the immune response.

A

Lymphocytes

39
Q

Two different types of lymphocytes

A

T cells (viruses) and B cells (bacteria)

40
Q

The largest sized WBC and produce macrophages

A

Monocytes

40
Q

These are minute fragments of cells, each
consisting of a small amount of cytoplasm
surrounded by a cell membrane.

A

Platelets

41
Q

Platelets are produced in the red bone marrow from large cells called _________________

A

megakaryocytes

42
Q

Platelets play an important role in ____________ blood loss

A

preventing/prevents

43
Q

Blood that is lost must be replaced by
production of new blood or by a ___________

A

transfusion

44
Q

In preventing blood loss, this can seal up small breaks in blood vessels

A

Platelet plugs

45
Q

An immediate but temporary constriction of blood vessel that results when smooth muscle within the wall of the blood vessel contracts.

A

Vascular spasm

46
Q

When blood vessel is severely damaged blood clotting __________ results in the formation of a clot.

A

coagulation

47
Q
  1. Injury to a blood vessel causes inactive clotting factors to become activated due to exposed conn. tissue or release of thromboplastin
  2. Prothrombinase (clotting factor) is formed and acts upon prothrombin
  3. Prothrombin is switched to its active form thrombin
  4. Thrombin activates fibrinogen into its active form fibrin
  5. Fibrin forms a network that traps blood (clots)
A

Steps in Clot Formation

48
Q

Prevent clots from forming

A

Anticoagulants

49
Q

RBC membranes have _____________________ antigens on their external surfaces

A

glycoprotein

50
Q

Transfusion reactions occur when ________________ blood is infused

A

mismatched

51
Q

Universal blood donor

A

O type (specifically, O- type)

52
Q

Universal blood receptors

A

AB type (AB+)