BLOOD Flashcards
transports substances such as oxygen and nutrients throughout the body and participates in processes such as clotting and fighting infections.
BLOOD
It is the only fluid tissue in the body
blood
Blood is a complex connective tissue in which living blood cells are suspended in plasma
formed elements
a nonliving fluid in blood
plasma
Most of the reddish “pellet” at the bottom of the tube is erythrocytes or the formed elements that function in oxygen transport.
red blood cells
thin, whitish layer at the junction between the erythrocytes and the plasma
buffy coat
leukocytes act in various ways to protect the body
white blood cells
cell fragments that help stop bleeding
platelets
Erythrocytes normally account for about 45 percent of the total volume of a blood sample, a percentage known as the
hematocrit (“blood fraction”)
White blood cells and platelets contribute
less than 1 percent
plasma makes up most of the remaining of the whole blood
55 percent
blood varies from color scarlet
oxygen-rich
blood color is dull red or purple
oxygen-poor
Blood is slightly alkaline, with a pH between
7.35 and 7.45
blood temperature
38°C, or 100.4°F
which is approximately 90 percent water, is the liquid part of the blood.
plasma
are the most abundant solutes in plasma.
Plasma proteins
acts as a carrier to shuttle certain molecules through the circulation, is an important blood buffer, and contributes to the osmotic pressure of blood, which acts to keep water in the bloodstream.
albumin
help stem blood loss when a blood vessel is injured
Clotting proteins
help protect the body from pathogens
antibodies
make dozens of adjustments day in and day out to maintain the many plasma solutes at life-sustaining levels
Various body organs
90% of plasma volume; solvent for carrying other substances; absorbs heat
water in plasma
Osmotic balance, pH buffering, regulation of membrane permeability
Salts (electrolytes)
Osmotic balance, pH buffering
Albumin
Plasma proteins
Albumin
Fibrinogen
Globulins
Salts (electrolytes)
Sodium
Potassium
Calcium
Magnesium
Chloride
Bicarbonate
Defense (antibodies) and lipid transport
Globulins
Clotting of blood
Fibrinogen
Functions: Defense and immunity
Leukocytes (WBC)
Functions: Blood clotting
Platelets
Functions: Transport oxygen and help transport carbon dioxide
Erythrocytes (RBC)
RBCs are anucleate that is, they lack a nucleus.
TRUE
an iron-bearing protein, transports most of the oxygen that is carried in the blood.
Hemoglobin (Hb)
what happen when the number of RBC/mm3 increases
blood viscosity, or thickness, increases
what happen when number of RBCs decreases
blood thins and flows more rapidly
A decrease in the oxygen carrying ability of the blood, whatever the reason, is called
anemia
the body does not form normal hemoglobin, Instead, abnormal hemoglobin is formed that becomes spiky and sharp
sickle cell anemia (SCA)
Only individuals carrying two copies of the defective gene have sickle cell anemia. Those carrying just one sickling gene have
sickle cell trait (SCT)
An excessive or abnormal increase in the number of erythrocytes, may result from bone marrow cancer
polycythemia
Genetic defect leads to abnormal hemoglobin, which becomes sharp and sickle-shaped under conditions of increased oxygen use by body; occurs mainly in people of African descent
Abnormal hemoglobin in RBCs
are far less numerous than red blood cells, they are crucial to body defense.
leukocytes, or white blood cells (WBCs)
form a protective, movable army that helps defend the body against damage by bacteria, viruses, parasites, and tumor cells
leukocytes
a process where white blood cells, by contrast, are able to slip into and out of the blood vessels
diapedesis
WBCs can locate areas of tissue damage and infection in the body by responding to certain chemicals that diffuse from the damaged cells.
positive chemotaxis
Once they have “caught the
scent,” the WBCs move through the tissue spaces
by
amoeboid motion
A total WBC count above 11,000 cells/mm3
is referred to
as leukocytosis
an abnormally low WBC count, It is commonly caused by certain drugs, such as corticosteroids and anticancer agents.
leukopenia
literally “white blood,” the bone marrow becomes cancerous, and huge numbers of WBCs are turned out rapidly.
leukemia
WBCs are classified into two major groups
granulocytes and agranulocytes