Block 1 Exam Flashcards
Vaccines
Live attenuated, Killed, & Subcellular
Live = a weakened organism without its pathogenicity is injected to trigger an immune response via IgA + IgG production. It lasts longer but can’t be given to immunocompromised patients because its potential to revert back to its pathogenic form
EX. MMR
Killed= Are good for short-term immunizations, dead organisms with low immunogenicity, but it still elicits an immune response to produce IgG’S
EX. Cholera, typhoid fever
Subcellular= Only the purified antigen; these are okay for AIDs patients
polysaccharide capsulated: Neisseria meningitides, Haemophilus influenza, streptococcus pneumonia,
Transplantation/Allograft Rejection
Acute vs. Chronic “4 CARs Vroom”
Acute= happens earliest at a week and is at highest risk for the first 3 months post transplant. Highly vascularized tissue tends to show signs first as T-cell mediated immunity leads to necrosis (primary response)
If the donor gives tissue again, the recipient could be at risk of an accelerated response (secondary) i.e tissue rejection in 3-5 days
Chronic= happens gradually months after the transplant, it is a type 4 hypersensitivity reaction that’s mediated by CD4+T’s, which cause chronic allograph vasculopathy (fibrosis of vasculature i.e occlusion/scarring)
Wiskott Aldrich syndrome “WATER WAS MuGy”
loss of CD43
“CANAIDian’s are POSITIVELY BUDDING”
Cancer markers “666” and first line of defence
“Fat MEN CaN’t get LAID”
“POSITIVE S.EX Is AMazing”
Candida albicans “CAP”
“PENIS”
Growth phases of bacteria
Lag= pregrowth period use dye
Log= exponential growth use penicillin
Stationary phase= Prime spore time
Death= waste becomes too toxic
“AC”
“3 POST StampS”
“Cardie G SANG”
“2 GP’s GIve Positive C-ANCA”
“Can DR’s Get More Brains”