bipolar/mania (2) Flashcards
describe duration of mania for classification
lasts at least 1 week for most of the day nearly every day
describe alterations that classify mania?
elevated, expansive, irritable, increased activity or energy, goal oriented
what is the hallamrk of mania?
flight of ideas
what are some of the signs/sx of mania?
-grandiosity
-decreased need for sleep
-more talkative
-flight of ideas
-distractibility
-goal-oriented
-psychomotor agitation
-excessive involvement
how can mania be emeregnt
increased suicide risk
can mania be attributed to substances or other conditions?
no
describe hypomania
less severe than regular/severe mania
-euphoric/increases functioning
-excessive activity
-not severe enough ti impair functioning or require hospitalization
-no psychosis with mania, may be present in depression
what disorders are characterized by mood swings from profound depression to extreme euphoria with intermittent periods of normalcy
bipolar disorders
what are the 3 types of bipolar disorders
bipolar 1
bipolar 2
cyclothymic
which bipolar disorder has a full syndrome of manic symptoms, alternates depression with anxiety and agitation, psychosis possible
bipolar 1
comorbidities with bipolar 1
anxiety, ADHD, impulse control, substance use
which bipolar disorder is major depression with episodic occurence of hypomania, has never met criteria for full manic episode
bipolar 2
comorbidities with bipolar 2
anxiety, eating disorders, subsyances
which bipolar disorder has symptoms of hypomania alternating with mild/moderate depressin for at least 2 years, does not meet other criteria - yet disturbing enough to alternate functioning
cyclothymic disorder
comorbidities with cyclothymic disorder
substance use disorder, sleep disorder, ADHD
describe rapid cycling in bipoalr disorder
4 mood episodes in 12 months, more severe and resistant to treament
bipolar used to be highly diagnosed in kids, but now is not. what is it called in kids now?
disruptive mood dysregualtion disorder (DMDD)
what is there a high risk for in undiagnosed bipolar teens?
suicide
is bipolar hereditary?
yes
biochemical influences of bipolar
excess norepi & dopamine, low serotonin
too much acetylcholine in depression, not enough in mania
what is lithium carbonate used for
antimanic, neuroprotective antisuicidal
contraindications of lithium
sodium depletion, dehydration, cardiac/renal disease, pregnancy/lactation
expected side effects of lithium
drowzy/dizzy/headache
dry mouth/GI upset
tremors
polyuria/dehydration
weight gain
what is the therapeutic range of lithium
0.6-1.2 mEq/L
at what level can lithium toxicity begin to be seen
1.5 mEq/L (HOLD MED AND CALL DR)
at what lithium level should a patient be hospitalized
2.0-2.5
describe fine tremors
expected, usually in hands, usually symmetric, can improve spontaneously
describe coarse tremors
SIGN OF TOXICITY, more irregular and severe, widespread, associated woth other symptoms
treatment of tremor
reduce caffeine, keep lithium levels low/medium, propranolol (beta blocker, HR/BP), vitamin B6
what does a person on lithium need to regularly intake
Na (salt) 2g
fluid intake for someone on lithium
1500-3000
what can anticonvulsants be used for?
mood stabilizers
what are the 3 main anticonvulsants used for mood stabilizers
valproic acid (depakene) / divalproex sodium (depakote)
lamotrigine (lamictal)
major side effect of anticonvulsants as mood stabilizers
liver failure
BBW for anticonvulsants as mood stabilizers
increased risk for suicidal thoughts and behaviors
therapeutic level of valproic acid
50-100 mcg/ml
at what level is valproic acid toxic
above 100 mcg/ml
BBW valproic acid
hepatotoxicity (monitor LFT/PLT)
what is the life threatening complication that comes from lamotrigine
rash, steven johnson syndrome
which meds work faster than mood stabilizers, so are used initially until drugs kick in
antipsychotics
what combo of meds must be given for bipolar depression
antidepressant and mood stabilizer
when monotherapy fails, what do yo udo?
augmentation with second med
when is ECT used for mania
meds are not tolerated or when life threatening behavior is present, depressive episodes with catatonia
what kinds of foods are best for manic patients
finger foods
what is a good way of controlling manic behavior
distraction