Bipolar Disorder Flashcards

1
Q

Define Hypomania

A

Briefer duration (at least 4 days) of manic symptoms
No psychosis
Mild functional impairment- can improve functioning
Out-patient

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2
Q

Define Mania

A
Longer duration (1+ week)
More severe symptoms
Pychosis
Significant impairment in functioning
Hospitalize
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3
Q

Subtypes of Bipolar Disorder

A

Bipolar 1

Bipolar 2

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4
Q

Define Bipolar 1

A

Hx of 1 manic episode with or without past major depressive episodes

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5
Q

Define Bipolar 2

A

Hx of at least 1 episode of major depression
Hx of at least 1 hypomanic episode
No Hx of manic disorder

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6
Q

Epidemiology of Bipolar I

A

Men = Women

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7
Q

Epidemiology of Bipolar II

A

Women > Men

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8
Q

Average Age of Onset of Bipolar Disorder

A

15-30

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9
Q

Clinical Course of Bipolar I

A

Relapses & remissions
Alternating pattern between manic & depressive episodes
90% have at least 1 hospitalization
Depressive episodes more frequent

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10
Q

Clinical Course of Bipolar II

A

Depressive symptoms more frequent than hypomanic episodes
Less marital depression
More likely at attempting & completing suicide

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11
Q

Co-morbidities with Bipolar Disorder

A

High rates of co-morbid ETOH or substance abuse
High risk for addictive disorder
Co-morbid anxiety disorder common
Many attempt suicide

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12
Q

Define Mixed State

A

Presence of both depressive & manic symptoms simultaneously

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13
Q

Experiences of a Mixed State

A
Impulsiveness
Insomnia
Irritability
Flight of ideas
Suicidal thoughts
Guilt
Feelings of hopelessness
Changes in appetite
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14
Q

What can mixed episodes lead to?

A

Panic attacks
Substance abuse
Suicide

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15
Q

Define Cyclothymia

A

Numerous periods of hypomania and of depression persisting for at least 2 years
Doesn’t meat DSM criteria for major depression

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16
Q

Treatment of Bipolar Disorder

A

Mood stabilizers: lithium, valproate, carbamazepine
Atypical antipsychotics: Quetiapine (Seroquel), risperidone (Risperdal), olanzapine (Zyprexa), ziprasidone (Geodon), clozapine (Clozaril)

17
Q

What two labs are critical to check when presenting with hypomania or mania?

A

Toxicology screen

Thyroid function tests

18
Q

Best option for PCP’s when diagnosing someone with bipolar disorder?

A

Refer to psychiatrist