Biotech Flashcards

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1
Q

What is a karyotype?

A

A visual, ordered display of all the chromosomes from one somatic cell

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2
Q

How is a karyotype made?

A

By taking pictures of chromosomes arranged by size, banding pattern, and centromere position.

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3
Q

What kind of mutations can karyotypes detect?

A

Chromosomal mutations and genetic disorders

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4
Q

What is nondisjunction?

A

Lack of correct chromosomal separation

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5
Q

What are the potential results of nondisjunction?

A

Disorders, miscarriage, possibility of death

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6
Q

What chromosome number would be found in gametes if nondisjunction occurs in Meiosis I?

A

22 and 24

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7
Q

What chromosome number would be found in gametes if nondisjunction occurs in Meiosis II?

A

22, 23, 24

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8
Q

Monosomy

A

2n-1

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9
Q

Trisomy

A

2n + 1

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10
Q

Which chromosome determines the sex of the baby?

A

X and Y chromosomes

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11
Q

Down syndrome

A

Extra copy of chromosome 21

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12
Q

Klinefelter

A

Extra X

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13
Q

Turner

A

Monosomy

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14
Q

What is colchicine?

A

A drug that inhibits microtubule formation

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15
Q

Why is colchicine used in the karyotype?

A

Freezes the chromosomes in Metaphase I because they are clearly visualized.

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16
Q

What is a Giemsa band?

A

Used to dye chromosomes so that their centromere positioning is clear for the karyotype.