Biopsychology - Ways of studying brain Flashcards

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1
Q

What are the 5 ways of studying the brain?

A
  • EEG (ElectroEncephaloGram)
  • ERP (Event Related Potentials)
  • Post mortem
  • fMRI (functional Magnetic Resonance Imaging)
  • PET (Positron Emission Tomography)
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2
Q

What is an EEG?

A
  • Electrical activity (“brain waves”) in the brain are recorded using electrodes placed on the scalp
  • The EEG records the electric impulses (action potentials) as neurons fire
  • Show patterns of activity which can be used diagnostically in epilepsy or to study mirror neurons or sleep for example
  • Each electrode produces its own reading so some vague localisation may be visible
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3
Q

What are examples of EEGs?

A

Mirror neuron research used to show areas that are active both when doing and watching a task.
This led to the broken mirror theory of autism.
Diagnostic tool in epilepsy treatment + research and sleep research.

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4
Q

What are the strengths of EEGs?

A
  • Measuring electrical activity from the brain is useful because the brain uses electrical impulses to operate.
  • Application to diagnosis of epilepsy and studying stages of sleep.
  • High temporal resolution (a millisecond).
  • Non invasive and risk-free.
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5
Q

What is the weakness of EEGs?

A

It can identify a general area of activity, but it cannot pinpoint specific areas of neuronal activity, so it may be less useful than other methods.

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6
Q

What is ERP?

A
  • Uses EEG equipment
  • ERPs are the measurement of small potential changes in the EEG signal immediately after the presentation of a sensory stimulus (event)
  • This makes it possible to record specific brain responses to sensory, motor, cognitive and other mental events
  • Show patterns of activity
  • These can be linked to specific processes such as attention and perception
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7
Q

What are the strengths of ERPs?

A
  • A form of EEG so shares the positives

- Provide more specific data on neural processes and allow for comparison of different ERPs and EEG.

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8
Q

What is the weakness of ERPs?

A

Can be difficult to use; background noise and other stimuli must be completely eliminated.

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9
Q

What is post mortem?

A
  • Dissection and examination of the brain after death
  • May involve observation of the gross structure of the brain, or the examination of slides of thin slices of the brain for microscope study; this is known as histology
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10
Q

What are the strengths of post mortem?

A
  • Historically very important

- Allows detailed study of structure which may be used to generate hypotheses for further studies on living brains

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11
Q

What are the weaknesses of post mortem?

A
  • Limited as it is structural rather than functional information
  • It is impossible to be sure about cause and effect (Broca’s patient Tan may have had speech problems because of a less obvious area of damage)
  • Ethics - issue of informed consent obtained from brain damage patients before death eg. HM’s brain was studied in post mortem
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12
Q

What are the examples of post mortem?

A

HM - thousands of slices were taken from his brain
Kitten’s visual cortex were studied after having one eye sewn shut
Tan - post mortem allowed identification of Broca’s area

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13
Q

What is fMRI?

A
  • Functioning magnetic resonance imaging
  • Measures blood flow = more oxygen = more activity in that part of the brain
  • Detects radio wave changes
  • Measurements are taken as the person performs a certain task, therefore functional
  • Allows for study of localisation of function
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14
Q

What are the strengths of fMRI?

A
  • Very high spatial resolution to 3 cubic mm or less, becoming more precise all the time
  • Non invasive and virtually risk-free
  • Compared to PET, it is safer as it does not use radiation
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15
Q

What are the weaknesses of fMRI?

A
  • The person must remain completely still for accurate results
  • Temporal resolution is poor - there is a 5 second time lag between the firing of a neuron and screen image
  • Measures blood flow not neuronal activity so exactly what sort of brain activity is represented is hard to know
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16
Q

What is PET?

A
  • Positron Emission Tomography
  • Radioactive isotope attached to glucose molecules; can be tracked in the brain
  • More glucose (more radiation = more activity)
17
Q

What are the strengths of PET?

A
  • Small movements do not affect the accuracy of PET scans, a clear advantage over fMRI scanning
  • So for example someone could read out words or answer questions while being PET scanned
18
Q

What are the weaknesses of PET scans?

A
  • PET scans are less precise than fMRI: 5-10 cubic millimetres compared to fMRI 3 cubic millimetres
  • PET scanning is much more expensive (special machines and isotopes) than fMRI
  • Invasive
  • Radioactive isotopes are used, these can be given only a few times before it is unsafe to do so
19
Q

What are the examples of where PET scans were used?

A

Adrian Raine: PET scans of pre-frontal cortex + amygdala in murderers compared to controls
Tulving: located episodic LTM - right PFC, semantic LTM - left PFC