Biopsychology- Plasticity and functional recovery Flashcards
Brain plasticity definition
Capacity of the brain to change and adapt (structure and function) in response to learning and experience
Synaptic pruning definition
Competing neutrons in your brain- latch onto synapse- 1st one gets nourished other falls away
As we age what happens to connections- what is this known as?
Rarely used connections are deleted, frequent ones are strengthened- (synaptic pruning)
Maguire et al (2000)- plasticity research
Procedure:
MRI scans used- 16 right-handed male London taxi drivers (>1.5 yrs driving)
Control Scanned- 50 healthy right-handed males didn’t drive taxis (comparison)
What design was Maguire study?
Independent group design
What experimental design was maguire?
Quasi- not directly manipulated independent variable
Maguire- plasticity findings
Increased grey matter in taxi (right + left hippocampi) compared to control
Found in posterior hippocampus (spatial awareness and navigation)
Longer in job- >structural difference
What can be inferred from maguire study?
More practise task, more brain adapts and changes
Maguire A03- validity
Population validity : low- male and London
Internal validity: high- standardised, very controlled
BUT individual differences (ppt variables affect?)
Maguire A03- correlational evidence + scanning
Correlational evidence: positive ( years driving and grey matter)- assuming is reason : could be learnt
Use of scanning: empirical, objective
What is functional plasticity/recovery?
The ability for brain to move functions from damaged area after trauma to undamaged area
What is neural reorganisation
Existing pathways inactive or used other purpose take over functions lost bc of injury
What is neuronal unmasking
Brain rewires and reorganises by forming new synaptic connections close to area of damage
What does spontaneous recovery mean
Process of functional recovery happens quickly after trauma and slows after weeks/months
What does the recruitment of homologous areas mean
Areas on opposite sides of brain take on tasks performed by damaged area- if has healed functions can return to normal
Functional recovery A03- research support
Danelli (EB case study)
- large tumour removed from left hemisphere 2.5 yrs old
-language disappeared
-began to improve even though almost all of left hemisphere was removed
-right hemisphere compensated for left
- recruitment of homologous areas
SUPPORTS BC BRAIN CAN REDISTRIBUTE FUNCTION TO UNDAMAGED AREAS
Danelli counter point:
Language caught up after 2.5 years- extensive and did not return to 100% so not immediate
-only 1 guy
- shouldn’t generalise findings bc unique case?
-idiographic
Functional recovery A03- Practical applications
-lead to neurorehabilitation (recover from brain damage)
- eg. Constraint- induced movement forces use of limb by restraint of other
-helps stimulate brain to quickly reorganise itself- encourages axon sprouting
CAN HELP MEDICAL PROFESSIONALS!!
Counter argument to brain adapting after trauma
- phantom limb syndrome 60% amputees
-neurological pain in limb that’s been amputated - no neural reorganisation or reorganisation has failed and led to negative consequences
WHAT EXTENT CAN PLASTICITY HAPPEN? MALFUNCTIONS ALONG THE WAY?