Biopsychology Flashcards

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1
Q

Localisation brain scan support

A

PETERSEN

Brain scan evidence:

  • Wernicke’s area active during listening task.
  • Broca’s area during reading task.

TULVING

Episodic and semantic memories in different areas of the prefrontal cortex.

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2
Q

Localisation (mental health) support

A

DOUGHERTY

  • Followed 44 OCD patients who had undergone cingulotomy (lesioning of cingulate gyrus)
  • After 32 weeks 1/3 successful response.
  • Symptoms localised.
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3
Q

Localisation (case study) support

A

PHINEAS GAGE (case study)

  • Pole took out left frontal lobe.
  • Became quick-tempered; personality change.
  • Left frontal lobe responsible for mood.
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4
Q

Localisation against

A

LASHLEY

  • Removed 10-50% of cortex in rats learning a maze.
  • No one area more important
  • More complex functions such as learning distributed holistically.
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5
Q

Plasticity in learning support

A

MAGUIRE

  • More grey matter in posterior hippocampus of London taxi drivers than control.
  • Test called ‘the knowledge’ causes learning changing brain structure.
  • Positive correlation between time in job and structural differences.

DRAGANSKI

  • Imaged brains of medical students 3 months before and after final exams.
  • Found changes in posterior hippocampus and parietal cortex.
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6
Q

Decreased plasticity with age against

A

BEZZOLA

  • 40 hours of golf training changed neural representation of movement in 40-60 year olds.
  • fMRI showed decreased activity in the motor cortex compared to control.
  • More efficient neural representation after training.
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7
Q

Plasticity after trauma

A

GIFFORDS (case study)

  • Shot in the head at point-blank range.
  • Made progress over time; gained complete control over left arm/leg, could write with right hand and read/understand/speak language.

HUBEL AND WEISEL

  • Sewed one eye of a kitten shut and analysed response of the brain,
  • Area associated with visual cortex of shut eye processed information from the other eye.
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8
Q

Increased plasticity with educational attainment

A

SCHNEIDER

  • Brian injury patients who spent more time in education had a better chance of disability-free recovery.
    1. Over 16 years = 40%
    2. Under 12 years = 10%
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9
Q

KEY STUDY: Sperry’s split-brain research

A

SPERRY

Procedure:

  • Sample of 11 epileptic patients who’d undergone a commissurotomy - corpus callosum and other connecting tissues cut.
  • Control group of 11 non-epileptic patients.
  • Image/word projected to right visual field (processed by left visual cortex).

Findings:

  1. Describing what’s seen - when image projected to left visual field (right visual cortex) reported nothing there; language centres in left hemisphere.
  2. Recognition by touch - when image projected to left visual field (right visual cortex) could select matching object with left hand. Could also select closely associated objects showing understanding.
  3. Composite words - when 2 different words projected to each hemisphere, would select object associated with right hemisphere and say word associated with left.
  4. Matching faces - when 2 different faces projected to each hemisphere, would select face matching right hemisphere. When a composite picture; 1 half to each hemisphere was used, the left hemisphere dominated in description and the right in selecting match.
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10
Q

Sleep/wake cycle

Endogenous pacemakers support

A

SIFFRE

  • Several extended periods underground without natural sound/light.
  • Resurfaced mid-September believing it to be mid-August.
  • Sleep/wake cycle regular but 25 hours.

FOLKARD

  • 12 ppts in dark cave for 3 weeks.
  • Bed when clock said 11:45pm and rose when 7:45am.
  • Sped up clock so ‘24hrs’ was 22hrs.
  • Only 1 ppt adjusted comfortably.
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11
Q

Menstrual cycle

A

STERN AND MCCLONTOCK

Procedure:

  • 20 ppts.
  • Samples of pheromones from women at different stages of cycle.
  • Cotton wool pad worn on armpit for 8 hours.
  • Pads treated with alcohol and frozen, to be rubbed on upper lip of ppts.
  • On day 1, pads from day 1 of cycle applied to all ppts, on day 2 pads from day 2 applied and etc.

Findings:
- 68% ppts experienced changes bringing them closer to ‘odour donor’.

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12
Q

Stages of sleep support

A

DEMENT AND KLEITMAN

Procedure:

  • 9 ppts monitored in sleep lab using EEG.
  • Controlled for effects of alcohol and caffeine.

Findings:

  • REM activity highly correlated with dreaming and brain activity varied according to how vivid dreams were.
  • Ppts woken during REM recalled dreams accurately.
  • Replications had similar findings.
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13
Q

Endogenous pacemakers support

A

SIFFRE

  • Maintained regular sleep/wake cycle without natural light/sound.
  • Cycle 25 hours long.

DECOURSEY

  • Destroyed SCN of 30 chipmunks.
  • Returned them to natural environment and observed for 80 days.
  • Sleep/wake cycle disappeared and most killed by predators.
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14
Q

Exogenous zeitgebers support

A

CAMPBELL AND MURPHY

  • 15 ppts woken at different times and light pad shone on back of knees.
  • Light detected by skin receptors when not reaching eyes.
  • Deviation in cycle of up to 3 hours.
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15
Q

Exogenous zeitgebers against

A

(case study - MILES)

  • Man born blind with sleep/wake cycle of 24.9 hours.
  • Couldn’t be adjusted.
  • Had to take sedatives and stimulants.

NB: those living in arctic regions have normal sleep/wake cycle despite prolonged light.

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