Biopsychology Flashcards
Localisation brain scan support
PETERSEN
Brain scan evidence:
- Wernicke’s area active during listening task.
- Broca’s area during reading task.
TULVING
Episodic and semantic memories in different areas of the prefrontal cortex.
Localisation (mental health) support
DOUGHERTY
- Followed 44 OCD patients who had undergone cingulotomy (lesioning of cingulate gyrus)
- After 32 weeks 1/3 successful response.
- Symptoms localised.
Localisation (case study) support
PHINEAS GAGE (case study)
- Pole took out left frontal lobe.
- Became quick-tempered; personality change.
- Left frontal lobe responsible for mood.
Localisation against
LASHLEY
- Removed 10-50% of cortex in rats learning a maze.
- No one area more important
- More complex functions such as learning distributed holistically.
Plasticity in learning support
MAGUIRE
- More grey matter in posterior hippocampus of London taxi drivers than control.
- Test called ‘the knowledge’ causes learning changing brain structure.
- Positive correlation between time in job and structural differences.
DRAGANSKI
- Imaged brains of medical students 3 months before and after final exams.
- Found changes in posterior hippocampus and parietal cortex.
Decreased plasticity with age against
BEZZOLA
- 40 hours of golf training changed neural representation of movement in 40-60 year olds.
- fMRI showed decreased activity in the motor cortex compared to control.
- More efficient neural representation after training.
Plasticity after trauma
GIFFORDS (case study)
- Shot in the head at point-blank range.
- Made progress over time; gained complete control over left arm/leg, could write with right hand and read/understand/speak language.
HUBEL AND WEISEL
- Sewed one eye of a kitten shut and analysed response of the brain,
- Area associated with visual cortex of shut eye processed information from the other eye.
Increased plasticity with educational attainment
SCHNEIDER
- Brian injury patients who spent more time in education had a better chance of disability-free recovery.
1. Over 16 years = 40%
2. Under 12 years = 10%
KEY STUDY: Sperry’s split-brain research
SPERRY
Procedure:
- Sample of 11 epileptic patients who’d undergone a commissurotomy - corpus callosum and other connecting tissues cut.
- Control group of 11 non-epileptic patients.
- Image/word projected to right visual field (processed by left visual cortex).
Findings:
- Describing what’s seen - when image projected to left visual field (right visual cortex) reported nothing there; language centres in left hemisphere.
- Recognition by touch - when image projected to left visual field (right visual cortex) could select matching object with left hand. Could also select closely associated objects showing understanding.
- Composite words - when 2 different words projected to each hemisphere, would select object associated with right hemisphere and say word associated with left.
- Matching faces - when 2 different faces projected to each hemisphere, would select face matching right hemisphere. When a composite picture; 1 half to each hemisphere was used, the left hemisphere dominated in description and the right in selecting match.
Sleep/wake cycle
Endogenous pacemakers support
SIFFRE
- Several extended periods underground without natural sound/light.
- Resurfaced mid-September believing it to be mid-August.
- Sleep/wake cycle regular but 25 hours.
FOLKARD
- 12 ppts in dark cave for 3 weeks.
- Bed when clock said 11:45pm and rose when 7:45am.
- Sped up clock so ‘24hrs’ was 22hrs.
- Only 1 ppt adjusted comfortably.
Menstrual cycle
STERN AND MCCLONTOCK
Procedure:
- 20 ppts.
- Samples of pheromones from women at different stages of cycle.
- Cotton wool pad worn on armpit for 8 hours.
- Pads treated with alcohol and frozen, to be rubbed on upper lip of ppts.
- On day 1, pads from day 1 of cycle applied to all ppts, on day 2 pads from day 2 applied and etc.
Findings:
- 68% ppts experienced changes bringing them closer to ‘odour donor’.
Stages of sleep support
DEMENT AND KLEITMAN
Procedure:
- 9 ppts monitored in sleep lab using EEG.
- Controlled for effects of alcohol and caffeine.
Findings:
- REM activity highly correlated with dreaming and brain activity varied according to how vivid dreams were.
- Ppts woken during REM recalled dreams accurately.
- Replications had similar findings.
Endogenous pacemakers support
SIFFRE
- Maintained regular sleep/wake cycle without natural light/sound.
- Cycle 25 hours long.
DECOURSEY
- Destroyed SCN of 30 chipmunks.
- Returned them to natural environment and observed for 80 days.
- Sleep/wake cycle disappeared and most killed by predators.
Exogenous zeitgebers support
CAMPBELL AND MURPHY
- 15 ppts woken at different times and light pad shone on back of knees.
- Light detected by skin receptors when not reaching eyes.
- Deviation in cycle of up to 3 hours.
Exogenous zeitgebers against
(case study - MILES)
- Man born blind with sleep/wake cycle of 24.9 hours.
- Couldn’t be adjusted.
- Had to take sedatives and stimulants.
NB: those living in arctic regions have normal sleep/wake cycle despite prolonged light.