Biology: cell communication Flashcards
How is “fight or flight” based on cell signaling?
epinefrin
Draw an example of a G-protein coupled receptor. What percent of medicines work in this manner?
60 percent medicine t, n
What are some diseases caused by errors or problems with the G-protein pathway
Draw an Ion gated channel receptor and explain how it can be turned on/off
What is an Receptor Tyrosine Kinase (RTK) and how does it work?
two receptors
Does a receptor tyrosine kinase activate one or many cellular responses?
many cellular responses because they are highly specific
What are the responses most often associated with RTKs?
Cell growth and reproduction (stimulate signals)
What is a Phosphorylation cascade?
chain of proteins that gets activated (expands out, amplification), phosphate added to first molecule and it is passed on to different proteins on the line and it can signal other phosphates. Which changes shape
How does a second messenger work?
send a message from one cell to another. Intracellular and promotes secondary message which gets a response. (non protein, CAMP, Calcium)
Why would it be important to a cell or organism to have signal amplification?
it can turn a small signal into a large response very quickly
What is apoptosis
a process in which a damaged cell, or a cell near the end of its life cycle breaks down its cellular components and dies
In dogs there can be a deficiency in the Tyrosine development in early embryos. What describes a dog that has inherited this efficiency?
A small dog because tyrosine is part of RTK and also used for growth. If tyrosine isn’t enough the growth hormone would not work
How does a scaffolding protein increase efficiency
take several transport proteins and take them with it which increases rate of reaction and decrease blockage
Why would apoptosis require integration of multiple signaling pathways?
shut down each system as you go. so the cell gets a signal to make sure it dies
explain how cyclins work and cyclin dependant kinases
phosphorylates only if there is cyclins - regulate cell life cycle (messaging molecule).